نتایج جستجو برای: fibroblast growth factor 1

تعداد نتایج: 3851213  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1992
S Werner K G Peters M T Longaker F Fuller-Pace M J Banda L T Williams

Recent studies have shown that application of basic fibroblast growth factor (basic FGF) to a wound has a beneficial effect. However, it has not been assessed whether endogenous FGF also plays a role in tissue repair. In this study we found a 160-fold induction of mRNA encoding keratinocyte growth factor (KGF) 1 day after skin injury. This large induction was unique within the family of FGFs, s...

Journal: :American journal of physiology. Lung cellular and molecular physiology 2000
C M Li J Khosla I Pagan P Hoyle P L Sannes

Fibroblast growth factor (FGF)-2, which stimulates DNA synthesis by type II cells in the lung, has been shown to be regulated by transforming growth factor (TGF)-beta1, an important inflammatory cytokine, in vascular epithelium. The goal of this study was to determine if FGF-2 production by alveolar type II cells is modulated by TGF-beta1 or FGF-1, which also stimulates DNA synthesis by type II...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2000
S Song M G Wientjes Y Gan J L Au

Based on the observation that removal of tumors from metastatic organs reversed their chemoresistance, we hypothesized that chemoresistance is induced by extracellular factors in tumor-bearing organs. By comparing chemosensitivity and proteins in different tumors (primary vs. metastases) and different culture systems (tumor fragment histocultures vs. monolayer cultures derived from the same tum...

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