at present, liver transplantation remains the only curative option for the patients with cirrhosis and end-stage liver diseases. the survival rate and recurrent diseases remain the major issues in the patient post-transplantation. unani medicine is one of the oldest traditional systems of medicine which has been treating chronic liver diseases and cirrhosis (talayyaful-kabid) for centuries. the...

Background and Aim: There is no data on the efficacy of 16:8, time-restricted feeding (TRF) intermittent fasting (IF) regimen in improving liver disease patients with NAFLD. The aim present study was to compare effectiveness calorie restriction by IF (16:8, TRF) standard care calorie-restriction (SOC) hepatic steatosis, inflammation fibrosis Methods: In this open label randomized study, 68 over...

Many studies used non-invasive methods to estimate the prevalence of significant fibrosis and its risk factors in patients with HIV infection. We evaluated the ability of APRI and FIB-4 score to differentiate between the different stages of fibrosis (no fibrosis/minimal fibrosis = F0-F1 and F2-F4 fibrosis moderate-severe/cirrhosis), taking as a reference, in the absence of liver biopsy, the hep...

Background and Aim: Non-Alcoholic Steatohepatitis is a common cause of chronic liver disease has emerged as major global health problem. Obeticholic acid, farnesoid X receptor agonist been shown to improve the histological features NASH. The interim analysis REGENERATE trial significant improvement after 25 mg OCA. We have conducted prospective study with 20 OCA in NASH patients. primary object...