Non-targeted effects can induce responses in tissues that have not been exposed to ionizing radiation. Despite their relevance for risk assessment, few studies have investigated these effects in vivo. In particular, these effects have not been studied in context with thyroid exposure, which can occur e.g. during irradiation of head and neck tumors. To determine the similarity between in-field a...

BACKGROUND Neoadjuvant chemoradiotherapy following surgery has recently become a standard therapy. The purpose of the present study was to determine the effectiveness and toxicity of re-irradiation for oligo-recurrence in lymph nodes from esophageal cancer treated by definitive radiotherapy or by surgery with additional radiotherapy. METHODS We reviewed retrospectively 248 patients treated wi...

BACKGROUND Bone-related complications are commonly reported in cancer patients receiving radiotherapy and are collectively referred to as the abscopal effect of irradiation, the mechanism of which remains poorly understood. When patients receive targeted radiotherapy to a tumor, the local skeleton is exposed to radiation, particularly within the bone marrow. We therefore investigated the hypoth...

Irradiation may have a profound effect on reproductive function. The schedule of the delivered irradiation (total dose, number of fractions, and duration) is an important determinant of the radiobiological effect on the tissues involved and varies among different tissues and organs. Irradiation to the central nervous system may affect the timing of the onset of puberty, result in hyperprolactin...

In recent times efforts are being made to improve the productivity of bambara groundnut. Studies were initiated (i) to characterise and evaluate landraces and to select superior ones for irradiation, (ii) to induce genetic variation through gamma irradiation and (iii) to use biotechnological approaches to shorten the generation cycle. The results of the study indicated that gamma irradiation in...

Due to acute and particularly chronic postirradiation complications in radiotherapy of the prostate, the dose application, and consequently also the irradiation effect, are restricted. The incidence and grade of acute and chronic complications depend upon the dose and volume of the surrounding organs involved in the irradiation area.1-4 As the restrictions on dose application should in no way b...

Nanoporous structures have a great potential for application in electronic and photonic materials, including field effect transistors, photonic crystals, and quantum dots. The control of size and shape is important for such applications. In this study, nanoporous structure formation on the indium antimonide (InSb) surface was investigated using controlled focused ion beam irradiation. Upon incr...

Conventional hard or dynamic wedge systems are commonly applied to reduce the dose inhomogeneity associated with whole breast irradiation. We evaluated the dosimetric benefits of the field-in-field (FIF) technique by comparing it with the electronic compensator (EC), Varian enhanced dynamic wedge (EW) and conventional hard wedge (HW) techniques. Data were obtained from 12 patients who had under...

BACKGROUND The aim of the present analysis was to evaluate the recurrence pattern in patients with recurrent malignant glioma after re-irradiation in combination with bevacizumab as there is limited data on how to optimally choose dose, fractionation and delineation margins. METHODS Thirty-one patients with recurrent malignant glioma treated with re-irradiation and bevacizumab after previous ...