The question when to initiate dialysis is attracting increasing attention. In recent years, there has been a tendency to initiate dialysis earlier in terms of estimated glomerular filtration rate (eGFR) in an attempt to achieve better patient outcomes. However, several observational studies and one randomized controlled trial have found no benefit for early dialysis initiation. On the contrary,...

To express growth-related changes in physiologic or other functions in forms usable for kinetic modeling, we are interested in identifying regular relationships that take the form of simple mathematical expressions. Many anatomic and physiologic functions scale within or across species in accordance with the allometric relationship, y = axb. These include many organ weights, the glomerular filt...

Objective Selective angioembolization (SAE) effectively diagnoses and treats iatrogenic vascular complications following percutaneous nephrolithotomy (PCNL). Methods We retrospectively reviewed 1329 consecutive PCNLs and identified patients who underwent SAE following PCNL with at least 12-month follow-up. Estimated glomerular filtration rate (eGFR) was calculated for all patients preoperativ...

The link between changes in a subject's metabolic syndrome components and her estimated glomerular filtration rate (eGFR) was evaluated in healthy Japanese women. We used data for 53 Japanese women (46.0±10.9 years) with a 1-year follow up. eGFR was defined by a new equation developed for Japan. There were no significant relationships between eGFR and clinical parameters at baseline. Subjects w...

The retrospective study was carried out to examine performance of Pottels height- independent equation compared to Schwartzs height-dependent equation to estimate glomerular filtration rate in 115 children in Indian setting. The Pottels equation performed well compared to updated Schwartz equation (R2=0.94, mean bias 0.25, 95% LOA=20.4, -19.9). The precision was better at lower range of estimat...

It has previously been shown that inulin clearance, diodrast clearance, and diodrast Tm are significantly lower in males between the ages of 60 and 80 years than in males 20-40 years of age (1, 2). The clearance and Tm values commonly used as norms are based on averages calculated from observations made on subjects between the ages of 17 and 68 years (3-5). The present study was undertaken to e...

This review summarizes the available evidence concerning the relationship between renal dysfunction and cardiovascular risk in non-diabetic patients. Based on numerous studies, there remains no more doubt today, that even minor renal dysfunction, as reflected by microalbuminuria and/or decreased estimated glomerular filtration rate, causes a dramatic increase in cardiovascular risk. Renal dysfu...