This study presents the first application of the model-free analysis (MFA) (Meiler in J Am Chem Soc 123:6098-6107, 2001; Lakomek in J Biomol NMR 34:101-115, 2006) to methyl group RDCs measured in 13 different alignment media in order to describe their supra-tau (c) dynamics in ubiquitin. Our results indicate that methyl groups vary from rigid to very mobile with good correlation to residue type...

A review of material flow analysis (MFA) tools, comparison of case studies and analysis of approximately 20 MFA tools (static, semi-empirical models) are performed. The evaluation of the quantification procedures revealed several deficits in the approaches. The following principal complications for a reliable quantification of inputs from the urban water system are identified: (1) frequently in...

Cuvier's beaked whales (Ziphius cavirostris) are known as extreme divers, though behavioral data from this difficult-to-study species have been limited. They are also the species most often stranded in association with Mid-Frequency Active (MFA) sonar use, a relationship that remains poorly understood. We used satellite-linked tags to record the diving behavior and locations of eight Ziphius of...

Today's technology development in the field of computer along with internet of things made huge difference in the transformation of our lives. Basic computer framework and web client need to make significant login signify getting to mail, long range interpersonal communication, internet keeping money, booking tickets, perusing online daily papers, and so forth. The login user name and secret ke...

Achieving better understanding phosphorus (P) flows through urban ecosystems is needed to conserve P, as non-renewable phosphate rock deposits become depleted and the global human population increases. A baseline mass flow analysis (MFA) for P developed for the Twin Cities Watershed (TCW, which includes most of the Minneapolis-St. Paul metropolitan region) showed that most P input was stored in...

During the past decade, BFA, a lipophilic funga1 toxin, has become a major tool of cell biologists interested in studying vesicle-mediated trafficking in animal and plant cells. Its main attractions include its ability to block secretion and to induce profound morphological changes in the organelles of the secretory and endocytic pathways in a totally reversible manner. In the plant literature,...

This study, encompassing 231 countries and regions, quantifies the global transfer of three critical metals (neodymium, cobalt, and platinum) considered vital for low-carbon technologies by means of material flow analysis (MFA), using trade data (BACI) and the metal contents of trade commodities, resolving the optimization problem to ensure the material balance of the metals within each country...

Mobile devices may act as support tools to achieve a balance between the technologic world and a physically active life, through the use of Mobile Fitness Applications (MFA), for example. However, keeping a long-term routine of exercising, even with the support of MFAs, demands high levels of motivation. In this paper we present an analysis of how MFAs with support for jogging and running have ...

A good fit of model predictions to empirical data are often used as an argument for model validity. However, if the model is flexible enough to fit a large proportion of potential empirical outcomes, finding a good fit becomes less meaningful. We propose a method for estimating the proportion of potential empirical outcomes that the model can fit: Model Flexibility Analysis (MFA). MFA aids mode...