To perform remote and direct sampling for mass spectrometry, solid probe assisted nanoelectrospray ionization (SPA-nanoESI) has been newly developed. After capturing the sample on the tip of the needle by sticking it to the biological tissue, the needle was inserted into the solvent-preloaded nanoESI capillary from the backside. NanoESI gave abundant ion signals for human kidney tissues and the...

Repeated biopsy sampling from one muscle is necessary to investigate muscular adaptation to different forms of exercise as adaptation is thought to be the result of cumulative effects of transient changes in gene expression in response to single exercise bouts. In a crossover study, we obtained four fine needle biopsies from one vastus lateralis muscle of 11 male subjects (25.9 ± 3.8 yr, 179.2 ...

background and objective: fine needle aspiration cytology (fnac) is a well-established method of diagnosis in palpable masses of various sites. this study was conducted to evaluate the usefulness of fnac as a diagnostic tool in the management of patients with cervical lymphadenopathy. patients and methods: totally 178 patients admitted to loghman-hakim hospital , tehran, iran, with cervical mas...

Introduction. Splenic tumor is usually found as an incidental finding on CT of abdomen. Traditionally, ultrasound (US) or computed tomography (CT) guided biopsies were employed for the purpose of sampling; however they have been reported to have a complication rate of 5.3%. Endoscopic ultrasound-fine needle aspiration (EUS-FNA) has been recently utilized for the purpose of sampling splenic tumo...

BACKGROUND AND STUDY AIMS A new 25-gauge (G) endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) device (EchoTip ProCore; Cook Medical, Bloomington, Indiana, USA) has been developed, which features a hollowed-out reverse bevel to trap core samples. However, data on the differences between the diagnostic yield of the 25G EchoTip ProCore and that of a 22G standard needle are limited. ...

RM The primary goal of fine-needle aspiration is to acquire individual cells as opposed to tissue, which is the aim of fine-needle biopsy. Cells may not necessarily provide the stroma, or the associated architecture, of the surrounding tissue. Thus, if the surrounding architecture is needed to make a diagnosis, a fine-needle biopsy, which typically uses a core biopsy needle, should provide that.

OBJECTIVE The use of Fine Needle Aspiration Cytology (FNAC) in the investigation of goitres was introduced into our practice more than a decade ago. This is a review of its diagnostic accuracy for thyroid carcinoma seven years after the first evaluation and following the establishment of the 'FNAC Clinic'. METHOD This is a retrospective study of patients who had FNAC of goitres and the histop...

cutaneous leishmaniasis(cl) is referred to a group of diseases because of the varied clinical presentation, ranging from small cutaneous nodule to wide spread mucosal destruction. the nose is rarely involved by cl in even in endemic region. in this report we describe a rare rhinophymatous presentation of cl from a non-endemic region which was diagnosed by fine needle sampling and treated with m...

Cutaneous leishmaniasis(CL) is referred to a group of diseases because of the varied clinical presentation, ranging from small cutaneous nodule to wide spread mucosal destruction. The nose is rarely involved by CL in even in endemic region. In this report we describe a rare rhinophymatous presentation of CL from a non-endemic region which was diagnosed by fine needle sampling and treated with M...

In 100 consecutive patients ultrasonically guided histological and cytological fine needle biopsy specimens were obtained from pancreatic lesions using two different needles with an outer diameter of 0.6 mm. Specimens taken by both cytological and histological fine needle biopsy were examined blindly by two pathologists. When related to the final and reliable diagnosis obtained in 57 patients, ...