The present review on floating drug delivery systems (FDDS) is aimed to compile the recent literature with special focus on the principal mechanism of floatation to achieve gastric retention. The recent developments of FDDS such as physiological and formulation variables affecting gastric retention, approaches to design single-unit and multiple-unit floating systems, and their classification an...

The most common spectrophotometric reagents employed for the determination of titanium (IV) are hydrogen peroxide[1] and tiron[2]. However, N-benzoylN-phenylhydroxylamine[3,4] and N-phenyllaurohydroxamic acid[5] are introduced for extractive spectrophotometric determination of titanium (IV). Aroylhydraones such as pyridoxal salicyloylhydrazone[6], diphenylglyoxal bis (benzoylhydrazone)[7] and d...

This paper describes zeroand first-order derivative spectrophotometric methods for determination of estradiol valerate in pharmaceutical preparations. The solutions of the standard and pharmaceutical samples were prepared in methanol. Absorbances of estradiol valerate were measured at 280 nm for zero-order by measuring height of peak from zero, at 292 nm for first-order derivative spectrophotom...

Simple, fast and reliable derivative spectrophotometric methods were developed for determination of olanzapine in bulk and pharmaceutical dosage forms. The solutions of standard and the sample were prepared in methanol. The quantitative determination of the drug was carried out using the first derivative values measured at 222 nm and the second derivative values measured at 230 nm (n=6). Calibr...

Non-derivative and derivative UV spectrophotometric techniques using water as solvent have been developed for the simultaneous determination of amoxicillin and clavulanate in combined tablets. For UV spectrophotometric techniques, the concentrations of amoxicillin and clavulanate in conformity with the Lambert-Beer law are 100.0 – 160.0 mg/ml and 10.0 – 35.0 mg/ml, respectively. The derivative ...

background: cryptosporidium parvum causes severe gastroenteritis in immunocompromised human and new borne animals. the organism can be transmitted through water. since small number of c. parvum is infectious, the aim of the present study was to develop a chromatography method for the isolation of c. parvum oocyst in samples with limited number of oocysts. methods: antibody was prepared against ...

A. Introduction B. Optical and Spectrophotometric Detectors 1. Differential refractometry 2. Ultraviolet spectrophotometry 3. Fluorescence detection 4. Infrared spectrophotometric detectors 5. Spectrophotometric detection with post-column chemical reaction C. Some Miscellaneous Detection Systems 1. The mass spectrometer as an HPLC detector 2. Radioactivity detectors 3. Density, electrochemical ...

Ten per cent of the general adult population have a diagnosable personality disorder (Zimmerman & Coryell, 1990)and in 4% this is clinically severe (Tyrer, 1988). The clinical management of such patients may be difficult. However, much clinical difficulty is generated by interpersonal aspects deriving from the particular interaction of the patient and psychiatrist involved and the respec tive r...