purpose: to investigate the results of deep lamellar keratoplasty (dlk) by big bubble method with using shifting bubble sign in patients suffering from keratoconus or corneal opacity methods: in this prospective interventional clinical trial, 20 eyes of 18 patients (10 males and 8 females) who underwent dlk by big bubble method using shifting bubble sign were investigated. mean age of cases wer...

Digital signature schemes often use domain parameters such as prime numbers or elliptic curves. They can be subject to security threats when they are not treated like public keys. In this paper we formalize the notion of “signature scheme with domain parameter” together with a new adversarial model: the “domain parameter shifting attack”. We take ECDSA as a case study. We make a domain paramete...

BACKGROUND Set-shifting is impaired in people with anorexia nervosa (AN), but the underlying physiological and biochemical processes are unclear. Animal studies have established that glutamatergic pathways in the prefrontal cortex play an important role in set-shifting ability. However, it is not yet understood whether levels of serum glutamatergic amino acids are associated with set-shifting p...

Biological studies into antidepressant drug action and into the aetiology of depression were highly active areas of research in the 1960s and 1970s but, arguably, have now lost some of their impetus and direction. Many investigations seem to have come to a natural end and there is a need for the subject to make a quantum leap to promote its development. It is recognized however, that advances h...

A region of the brain called the putamen has a central role in procedural memory consolidation during sleep.

Switching between mental sets has been extensively investigated in both experimental and individual differences research using a wide range of task-switch paradigms. However, it is yet unclear whether these different tasks measure a unitary shifting ability or reflect different facets thereof. In this study, 20 task pairs were administered to 119 young adults to assess 5 proposed components of ...

This paper describes a novel method of calculating the sensitivity of the manufacturing system throughput to the variables of the machines. The sensitivity analysis needs only a single simulation, yet is easy to use and provides accurate results. This sensitivity analysis is then used to predict the change in the system throughput due to a change of the variables of the machines provided that t...

Audio time stretching and pitch shifting are operations that all major commercial and/or open source Digital Audio Workstations, DJ Mixing Software and Live Coding Suites offer. These operations allow users to change the duration of audio files while maintaining the pitch and vice-versa. Such operations enable DJs to speed up or slow down songs in order to mix them by aligning the beats. Unfort...