Amide-benzothiazole based receptors act as highly selective chemosensors for Cu(ii) and Zn(ii) ions both in solution and in the solid state. Binding and crystallographic studies have been used to shed light on the mechanism of interaction between chemosensors and metal ions.

The development of fluorescent sensors for Hg2+ has attracted much attention due to the well-known adverse effects of mercury on biological health. In the present work, the optical properties of two newly-synthesized Hg2+ chemosensors based on the coumarin-rhodamine system (named Pro1 and Pro2) were systematically investigated using time-dependent density functional theory. It is shown that Pro...

Nonlinear optical properties of a series of newly-synthesized molecular fluorescent probes for Hg2+ containing the same acceptor (rhodamine group) are analyzed by using time-dependent density functional theory in combination with analytical response theory. Special emphasis is placed on evolution of the probes' optical properties in the absence and presence of Hg2+. These compounds show drastic...

In recent decades, concerns about increasing biological and environmental contamination have necessitated the development of chemosensors with high selectivity, sensitivity, cost-effectiveness. principle, sensing performance can be affected by functional group(s) receptor, charge metal ion(s), electron configuration molecule(s)e ion(s). Fine controlling substituents influence density receptor t...

The field of intestinal physiology has been transformed by the discovery that nutrient-sensitive chemosensors are strategically positioned within the gastrointestinal tract to regulate nutrient absorption and gut hormone secretion. It is well established that the composition of the diet modulates the absorptive capacity of the intestine and the secretion of gut peptides including glucoinsulinot...

Novel multifunctional switchable chemosensors based on fluorescent electrospun (ES) nanofibers with sensitivity toward magnetism, temperature, and mercury ions (Hg2+) were prepared using blends of poly(N-isopropylacrylamide)-co-(N-methylolacrylamide)-co-(Acrylic acid), the fluorescent probe 1-benzoyl-3-[2-(2-allyl-1,3-dioxo-2,3-dihydro-1Hbenzo[de]isoquinolin-6-ylamino)ethyl]-thiourea (BNPTU), a...

Acidity, hypoxia, and glucose levels characterize the tumor microenvironment rendering pH, pO2, and pGlucose, respectively, important indicators of tumor health. To this end, understanding how these parameters change can be a powerful tool for the development of novel and effective therapeutics. We have designed optical chemosensors that feature a quantum dot and an analyte-responsive dye. Thes...