Description: Fluoride dentifrices were first introduced in the 1950s. [1] The first fluoride dentifrice contained stannous fluoride and was first marketed in 1955. Since then many studies have investigated the level of dose and the form of fluoride that is optimum in dentifrice formulations. Higher caries reduction was reported in the 70s in clinical trials that investigated the potency of usin...

OBJECTIVE Presence of available and stable fluoride in a dentifrice formulation is a major requirement for an anti-caries effect. Although the available fluoride concentration in Iranian dentifrices has been reported in previous studies, there is little information on its stability; which is dependent upon dentifrice formulation. This study was done to assess the fluoride ion concentration and ...

presence of available and stable fluoride in a dentifrice formulation is a major requirement for an anti-caries effect. although the available fluoride concentration in iranian dentifrices has been reported in previous studies, there is little information on its stability; which is dependent upon dentifrice formulation. this study was done to assess the fluoride ion concentration and stability ...

Background and Objectives Herbal dentifrices are fast gaining popularity in most parts of Asia and Europe. Although effects of dentifrices on pathogenic plaque microorganisms has been documented, little or no evidence exists with regard to their effects on the useful microflora, which help to keep the pathogenic strains at bay. The present study was attempted to evaluate and compare these effec...

The utilization of dentifrices with low fluorine concentration, for children under 6 years of age, has been suggested to reduce the risks of dental fluorosis. However, in order to have anticariogenic potential, the dentifrice should form loosely-bound fluorine (CaF2) on dental enamel. Considering that the formation of CaF2 is a function inversely related to pH, dentifrices with pH 5.5, with 275...

This in situ/ex vivo study assessed the effect of different concentrations of fluoride in dentifrices on dentin subjected to erosion or to erosion plus abrasion. Ten volunteers took part in this crossover and double-blind study performed in 3 phases (7 days). They wore acrylic palatal appliances containing 4 bovine dentin blocks divided in two rows: erosion and erosion plus abrasion. The blocks...

It has been suggested that systemic fluoride absorption from drinking water may be influenced by the type of fluoride compound in the water and by water hardness. Using a human double-blind cross-over trial, we conducted this study to measure c(max), T(max), and Area Under the Curve (AUC) for plasma F concentration against time, following the ingestion of naturally fluoridated hard and soft wat...

OBJECTIVE To examine some of the potential benefits and risks of water fluoridation for older adults. METHODS This study used 'The Irish Longitudinal Study on Ageing', to access a nationally representative sample of 4977 people aged 50 and older. The sample was used to estimate associations between the percentage of households in a respondent's local area with a currently fluoridated water su...

OBJECTIVE To determine the clinical effectiveness of a community milk fluoridation programme. BASIC RESEARCH DESIGN Parallel arm 5-year cohort study, with final cross-sectional comparisons between groups. PARTICIPANTS 3-year-olds in 8 Bulgarian cities/towns entered the cohort study with random samples (n = 1,782) recruited at baseline in 2004. After 5 years in 2009 sub-samples (about 30%) o...

Fluoridated mouthrinses are not advised for preschool children who may swallow much of the agent. An alternate method of delivering topical fluoride to the interproximal tooth surfaces in these young patients may be fluoridated dental floss. The purpose of this study was to determine the fluoride levels of demineralized primary enamel both before and after the use of a commercially available de...