Biochemical methods originally designed for mammalian tissues are not, in all instances, directly adaptable to tissues from other species, such as fish. Consideration must be given to the biochemical profile of the research animal to which an analytical method is to be applied. In particular, when adapting a method for an amino acid such as phenylalanine from mammalian serum to fish serum, one ...

A simple and sensitive fluorimetric method for determination of antiviral drugs: ribavirin, acyclovir, and amantadine hydrochloride has been developed. The method was based on the oxidation of these drugs by cerium(IV) in presence of perchloric acid and subsequent monitoring the fluorescence of the induced cerium(III) at lambdaexcitation 255 and lambdaemission 355 nm. Different variables affect...

DNA quantification of soils and sediments is useful for the investigation of microbial communities and for the acquisition of their genomes that are exploited for the production of natural products. However, in such samples DNA quantification is impaired by humic acids (HA). Due to its lack of specificity and sensitivity, UV spectrophotometry cannot be applied. Consequently, fluorimetric assays...

Recognition of the association of paroxysmal a hypertension with phaeochromocytomata, actively I secreting tumours of the chromaffin tissue of the i adrenal medulla, has resulted in the need for more d careful scrutiny of hypertensive patients for evidence of this disease which, if found, may be cured by surgical removal of the growth. Much help in diagnosis may be obtained by the trial of prov...

Favipiravir is a synthetic prodrug, which was first discovered while assessing the antiviral activity of chemical agents active against influenza virus in library Toyoma chemicals. It works by inhibiting RNA dependant polymerase (RdRP), an enzyme required for viral replication inside human cells. A simple, rapid, and economic method developed quantitative determination Favipiravirusing spectrof...

New simple and sensitive spectrophotometric and fluorimetric methods have been developed for the determination of prazosin hydrochloride (PRZ) in its active pharmaceutical ingredient (API) and drug product. The spectrophotometric method (Method I) is based on formation of a binary complex with rose Bengal (RB) at 572 nm. The absorbance-concentration plot is rectilinear over the range 2.5 25 μg/...