Abstract Background The gene expression of anti-Mullerian hormone receptor type 2 ( AMHR2 ) and follicle stimulating (FSHR) in cumulus cells (CCs) isolated from mature immature oocytes was studied as a possible non-invasive approach for determining oocyte maturity quality. CCs 100 infertile women with different etiologic factors were subdivided into control (CCs MII) case GV) group. Q-PCR used ...

Background: Ovarian physiology illustrates the synergistic interaction between luteinizing hormone and follicle stimulating hormone in the process of folliculogenesis. While follicle stimulating hormone has been well established as a marker of ovarian reserve, the role of luteinizing hormone has remained somewhat controversial and it seems to have become the ‘forgotten gonadotropin’. The follow...

Parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP) influence hair follicles through paracrine and intracrine routes. There is significant evidence that PTH and PTHrP influence the proliferation and differentiation of hair follicle cells. The PTH/PTHrP receptor signalling plays an important role in the hair follicle cycle and may induce premature catagen-telogen transition...

Many hormones that are central to normal reproductive functioning mediate their physiological effects by activating a receptor which belongs to the large family of G-protein-coupled receptors (GPCR). Members of this family of receptor proteins are usually glycosylated on extracellular domains. In recent years the role of this glycosylation in cell surface expression/protein folding, ligand reco...

The objective of research was to determine the sensitivity, specificity and positive predictive value of serum follicle stimulating hormone and testis size in predicting spermatogenesis in infertile men with azoospermia. In a prospective study, azoospermic men were studied. Serum follicle stimulating hormone measurement and scrotal sac ultrasonography were performed. Bilateral testis biopsy was...

Some properties of the interaction between radioiodinated human follicle stimulating hormone (lz51-hFSH) and its specific receptors in preparations of rat seminiferous tubule homogenate are described. Specific binding of lz51-hFSH by seminiferous tubule homogenate was appreciably greater than to Leydig cell homogenate of rat testes. The uptake of rz51-hFSH was hormone specific and uptake inhibi...

OF DISSERTATION

BACKGROUND The purpose of this study was to compare Gonal-F(®), a recombinant follicle-stimulating hormone, with Menopur(®), a highly purified human menopausal gonadotrophin (hpHMG) in assisted reproduction in Greece. METHODS A decision tree in combination with a Markov model was used to assess the clinical and economical impact of comparators for up to three consecutive cycles. Transition pr...

OBJECTIVE The aim of this study was to investigate whether N680S FSHR polymorphism has a predictive value for the ovarian response to stimulation with gonadotropins and cycle outcome in our egg donor program. METHODS The oocyte donor candidates were selected according to the Instituto Bernabeu egg donation program requirements and ASRM and ESHRE guidelines for oocyte donation. The FSHR polymo...