Follicular development is controlled partly by intra-ovarian and intrafollicular factors within the ovary and partly by extra-ovarian events. Many oocyte derived factors and granulose cell factors are also involved in follicle development. A better understanding of all the processes involved in follicular development regulated by growth factors will develop procedures to enhance the reproductiv...

The objective of this study was to characterize the patterns of ovarian follicular waves, and FSH and P4 concentration during estrous cycle in Thai native cattle (Bos indicus). Transrectal ultrasound examination of ovaries was performed daily using a 7.5 MHz transducer and blood samples were collected after the ultrasound examination during May to August, 2010. There were 1-, 2or 3-follicular w...

background: the differential efficacy between long gnrh agonist with antagonist can partly be due to the preexisting differences in the early antral follicles before ovarian stimulation. objective: to compare the effect of pretreatment by estradiol with gnrh antagonist on antral follicular size coordination and basal hormone levels in gnrh antagonist protocol. materials and methods: on cycle da...

During the early follicular phase in the menstrual cycle, antral follicle sizes are often markedly heterogeneous. These follicular size discrepancies may, at least in part, result from the early exposure of FSH-sensitive follicles to gradient FSH concentrations during the preceding luteal phase. In addition, they potentially affect the results of ovarian stimulation. Indeed, pre-existing follic...

Growth and development of ovarian follicles require a series of coordinated events that induce morphological and functional changes within the follicle, leading to cell differentiation and oocyte development. The preantral early antral follicle transition is the stage of follicular development during which gonadotropin dependence is obtained and the progression into growing or atresia of the fo...

Follicles from goat and sheep ovaries were characterized for their biochemical and hormonal parameters to investigate the effect of developmental stage of follicles on ovarian steroidogenesis. The follicles were isolated mechanically from follicular and luteal phase ovaries and divided in 6 morphologically different groups (small, medium and large follicular and small, medium and large luteal)....

Introduction: The origin of neonatal oocyte development is unknown. However, estrogen plays an essential role during development of the female reproductive system. Anastrozole is used as both ovulation stimulating and an anticancer drug. The aim of this study was to evaluate the impact of Anastrozole on follicular development and differentiation in mice. Materials and methods: In the present s...

Follicular dendritic cells (FDC) show homo- and heterocellular metabolic coupling through connexin 43 (Cx43) gap junctions and support B cell selection and maturation in germinal centers. In follicular lymphomas B cells escape apoptosis while FDC develop abnormally. Here we tested Cx43 channels in reactive FDC development and follicular lymphomas. In culture, the treatment of FDC-B cell cluster...