Genetic analysis of the Drosophila Bloom's syndrome helicase homolog (mus309/DmBLM) indicates that DmBLM is required for the synthesis-dependent strand annealing (SDSA) pathway of homologous recombination. Here we report the first biochemical study of DmBLM. Recombinant, epitope-tagged DmBLM was expressed in Drosophila cell culture and highly purified protein was prepared from nuclear extracts....

In this paper, we examine algorithmic issues related to the delayed multicast technique for video-ondemand delivery. We introduce the minimum total memory (MTM), minimum total traffic (MTT) and the minimum maximum memory per node (MMMN) delayed-multicast allocation problems. We examine these problems on two networks of practical interest, namely, the chandelier and the broom networks. We provid...

A new concept of Agreement (AGR) has been represented as a Formal Feature that can appear in a wide range of different configurations (Chomsky, 1998). A case study from language disorders supports and extends this abstract concept. The child shows no agreement in Inflectional Phrase me can and Determiner Phrase them eyes. We then extend the notion of AGR to include verb-Prepositional Phrase rel...

We propose a method for measuring and quantifying image quality in push-broom hyperspectral cameras in terms of spatial misregistration caused by keystone and variations in the point spread function (PSF) across spectral channels, and image sharpness. The method is suitable for both traditional push-broom hyperspectral cameras where keystone is corrected in hardware and cameras where keystone i...

In very high-resolution (VHR) push-broom-type satellite sensor data, both destriping and denoising methods have become chronic problems and attracted major research advances in the remote sensing fields. Since the estimation of the original image from a noisy input is an ill-posed problem, a simple noise removal algorithm cannot preserve the radiometric integrity of satellite data. To solve the...

To enhance the inhibitory potential of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (ribavirin) vs hepatitis C virus (HCV) NTPase/helicase, ribavirin-5'-triphosphate (ribavirin-TP) was synthesized and investigated. Ribavirin-TP was prepared with the use of modified Yoshikawa-Ludwig-Mishra-Broom procedure (cf. Mishra & Broom, 1991, J. Chem. Soc., Chem. Commun, 1276-1277) involving phospho...

Pre-publication copy 1 Broom, D.M. 2013. The welfare of invertebrate animals such as insects, spiders, 2 snails and worms. In Animal Suffering: From Science to Law, International 3 Symposium, ed. Kemp, T. A. van der and Lachance, M., 135-152. Paris: Éditions 4 Yvon Blais. 5 THE WELFARE OF INVERTEBRATE ANIMALS SUCH AS INSECTS, 6 SPIDERS, SNAILS AND WORMS 7 8 D. M. Broom 9 10 ABSTRACT 11 The conc...

A model for cleaning a graph with brushes was recently introduced. Let α = (v1, v2, . . . , vn) be a permutation of the vertices of G; for each vertex vi let N (vi) = {j : vjvi ∈ E and j > i} and N−(vi) = {j : vjvi ∈ E and j < i}; finally let bα(G) = ∑n i=1 max{|N+(vi)|−|N−(vi)|, 0}. The Broom number is given by B(G) = maxα bα(G). We consider the Broom number of d-regular graphs, focusing on th...

Witches' broom of lime is a disease caused by Candidatus Phytoplasma aurantifolia, which represents the most significant global threat to the production of lime trees (Citrus aurantifolia). Conventional disease management strategies have shown little success, and new approaches based on genetic engineering need to be considered. The expression of recombinant antibodies and fragments thereof in ...