Zinc deficiency is a global nutritional disorder affecting majority of healthy people rather than those suffering from chronic diseases, affects about one third of people around the world and thereby causing clinical manifestations. This work represents new modality to increase the intestinal absorptivity and bioavailability of zinc from the diet by replacing traditional bulk form by zinc nanop...

Fig. 2. Sephadex G.75 elution profiles of kidney supernatants ofrats and mice injected with zinc. The kidney supernatants (10 ml/column) were applied to a Sephadex G-75 column, eluted with 1 mM Tris buffer solution (pH 8.6), and collected (5 ml/tube). -, Zn; and -, Cu. The arrow indicates the metallothionein fraction. RK and MK are abbreviated forms of rat kidney and mouse kidney, respectively....

Objective: Preparation and characterization studies on tetrahydrocurcumin complexed with zinc, particular reference to the location of zinc in complex. Methods: Structural characteristics its complex were compared using elemental analysis, mass spectrometry (MS), proton, carbon-13 nuclear magnetic resonance spectroscopy (NMR), ultraviolet-visible (UV) absorption spectroscopy, Fourier transform ...

Zinc is the second most abundant transition metal in the body. It is essential for most living beings. The human body contains approximately 2 g of zinc. It is mainly distributed in the blood, kidney, liver, bone, and brain. Zinc is a co-factor of more than 300 enzymes or metalloproteins. These zinc-related proteins play biologically important roles in mitotic cell division, protein synthesis, ...

PURPOSE OF REVIEW To evaluate clinical data indicating the benefits of oral zinc supplementation to prevent and/or treat diarrhea in children and extend these findings to adults. RECENT FINDINGS Zinc plays an important role in modulating host resistance to infectious agents and reducing the risk, severity, and duration of diarrheal diseases. Zinc is important in the developing world and in lo...

A Clostridium histolyticum 116-kDa collagenase has an H415EXXH motif but not the third zinc ligand, as found in already characterized zinc metalloproteinases. To identify its catalytic site, we mutated the codons corresponding to the three conserved residues in the motif to other amino acid residues. The mutation affecting His415 or His419 abolished catalytic activity and zinc binding, while th...