In this paper, we present two DRM formulations. For a pseudo–Poisson equation, if the right hand side is a linear operation on the dependent variable, we can derive a new DRM formulation. In comparison with the traditional DRM formulation for the same equation, the new one is much easier and more efficient. For the axisymmetric Poisson equation, we construct a DRM formalation by using the linea...

The discovery and development of a new drug can be a lengthy and expensive business (Fig. 1). The starting point is the active compound as synthesized by the medicinal chemist and screened by the pharmacologist. There then follows a series of complex tests and evaluations to produce a satisfactory formulation and sufficient data for presentation to regulatory authorities such as the Committee o...

The extension complexity of a polytope P is the smallest integer k such that P is the projection of a polytope Q with k facets. We study the extension complexity of n-gons in the plane. First, we give a new proof that the extension complexity of regular n-gons is O(logn), a result originating from work by Ben-Tal and Nemirovski (Math. Oper. Res. 26(2), 193–205, 2001). Our proof easily generaliz...

The author renders here an English translation to Lehdhyaya of the Kasyapa-samhita, Suthrasthana, 1-6.

The present investigation includes the preparation of liquid filling formulations for soft gels using an antihypertensive drug, valsartan (VAL), in order to improve its dissolution properties and thereby its bioavailability. Formulations were prepared using excipients like polyethylene glycol 400 (PEG 400), propylene glycol (PG), polyvinylpyrrolidone (PVP K-30), antioxidants, ethanol, and purif...

Background: Several adjuvants have been evaluated for vaccine formulations but alu-minum salts will continue to be used for many years due to their safety, low cost and adjuvanticity with different antigens. Two commonly used aluminum adjuvants, alumi-num hydroxide and aluminum phosphate have different adjuvanticity properties. Com-mercial recombinant protein hepatitis B vaccines containing alu...

objective(s) the objective of this study was to prepare, characterize and evaluate the nanoliposomes containing safranal as a natural sunscreen and moisturizer factor. materials and methods the experimental formulations included homosalate reference, nanoliposomes containing 0.25, 0.5, 1, 2, 4 and 8% safranal and empty liposomes. the liposomes were prepared using fusion method and homogenizatio...

In this paper we make a comparative study of several mixed integer linear programming (MILP) formulations for resource-constrained project scheduling problems (RCPSPs). First, we present three discrete and continuous time MILP formulations issued from the literature. Second, instead of relying on the traditional discretization of the time horizon, we propose MILP formulations for the RCPSP base...

Psychological formulations are central to cognitive behavioural approaches. The use of such formulations presents a number of difficulties when working with clients with psychotic problems. Despite this, sophisticated psychological formulations can be collaboratively developed with psychotic clients. This paper presents one method of developing such formulations through an evolutionary process....

Experience in Queensland has shown that when crude BHC is refined to yield products containing higher proportions of the gamma isomer, the insecticidal persistence of the BHC in soil is decreased. This process also diminishes the specific toxicity of BHC to the soldier fly pest, Alfe~nzetopon.ia rubriceps (Macq.). I t also decreases the potential phytotoxicity, since less total BHC is required ...