The reaction of 17,17-dichloro-androst-16(E)-chloromethylene with secondary amine base afforded substitution products exocyclic D-ring ketones, in contrast to the alkaline which cleaved steroidal des-D formyl alkyne. alkyne was employed prepare annulated isoxazolo steroid via 1,3-dipolar nitrile oxide cycloaddition reaction.

Pure ices of amorphous methanol, CH3OH(X 1A0), were irradiated at 11 K by 5 keVelectrons at 100 nA for 1 hr. These energetic electrons simulate electronic energy transfer processes that occur as interstellar ices, comets, and icy solar system bodies are subjected to irradiation fromMeV ions and secondary electrons produced in this process. The results were analyzed quantitatively via absorption...

Melatonin, originally discovered as a hormone of the pineal gland, is also produced in other organs and represents, additionally, a normal food constituent found in yeast and plant material, which can influence the level in the circulation. Compared to the pineal, the gastrointestinal tract contains several hundred times more melatonin, which can be released into the blood in response to food i...

The pathways of propionate formation in the propionibacteria and of propionate oxidation in animal tissues have been well documented. In the bacteria the final step is the transfer of a carboxyl group from methylmalonyl CoAl to pyruvate with the formation of oxalacetate and propionyl CoA." I The reaction was found to involve biotin;2 the purified enzyme, methylmalonyl-oxalacetic transcarboxylas...

We studied the thermal decomposition of vanillin in a low-pressure pyrolysis microreactor by photoelectron photoion coincidence spectroscopy. The products were identified isomer-selectively mass-selected threshold spectra (ms-TPES) based on Franck–Condon simulations and reference spectra. Methyl loss homolytic C–O bond fission methoxy group is initial unimolecular step. primary intermediate, 2-...

Mibyou has been defined in traditional oriental medicine as a certain physiological condition whereby an individual is not ill but healthy; it also often referred to sub-healthy condition. In society focused on longevity, “Mibyou-care” becomes of primary importance for healthy lifespan expenditure. Functional foods can play crucial roles Mibyou-care; thus, the search novel resources functional ...

antioxidants are vital substances which possess the ability to protect the body from damage caused by free radical induced oxidative stress. a variety of free radical scavenging antioxidants exist within the body which many of them are derived from dietary sources like fruits, vegetables and teas. in this study the antioxidant activity and radical scavenging activity of methanolic extracts of s...