نتایج جستجو برای: four different molecular markers as nak atp

تعداد نتایج: 7065101  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه سمنان - دانشکده ادبیات و علوم انسانی 1393

this thesis is an evaluation of poetry of sylvia plath (1932- 1963) and forough farrokhzad (1935-1967) using feminist approach and finds the positive concepts of hope, reason and strength through feminine images in their poetry. plath and farrokhzad are from different cultures and different countries but they share the same concepts and themes in their poetry. by applying feminist theory to the...

Journal: :Journal of Physical Chemistry B 2021

The COVID-19 pandemic has demonstrated the need to develop potent and transferable therapeutics treat coronavirus infections. Numerous antiviral targets are being investigated, but nonstructural protein 13 (nsp13) stands out as a highly conserved yet understudied target. Nsp13 is superfamily 1 (SF1) helicase that translocates along unwinds viral RNA in an ATP-dependent manner. Currently, there ...

Journal: :iranian journal of basic medical sciences 0
ezzat dadkhah department of human genetics, immunology research centre, avicenna research institute, mashhad university of medical science, mashhad, iran masood ziaee birjand hepatitis research centre, birjand university of medical sciences, birjand, iran mohammad hossein davari ophthalmology department, vali-e-asr hospital, birjand university of medical sciences, iran toba kazemi birjand atherosclerosis and coronary artery research centre, birjand university of medical sciences, birjand, iran mohammad reza abbaszadegan department of human genetics, immunology research centre, avicenna research institute, mashhad university of medical science, mashhad, iran medical genetic research centre (mgrc), school of medicine, mashhad university of medical sciences, mashhad, iran

objective(s)marfan syndrome (mfs) is a severe connective tissue disorder withan autosomal dominant inheritance pattern. early diagnosis is critical in mfs. because of the large size of fibrillin-1 gene (fbn1), the uniqueness of mutations, and the absence of genotype-to-phenotype correlations linkage analysis can be very helpful for early diagnosis of mfs. in this study, eight polymorphic marker...

2015
Ziyi Guo Qiang Zhang Xiaoguang Li Zhengyu Jing

OBJECTIVE Alkali metal appears to be a promising tool in thermochemical ablation, but, it requires additional data on safety is required. The objective of this study was to explore the effectiveness of permeable oil-packed liquid alkali metal in the thermochemical ablation of tumors. METHODS Permeable oil-packed sodium-potassium (NaK) was prepared using ultrasonic mixing of different ratios o...

this thesis attempts to investigate the effects of prelistening activities on enhancing iranian efl learners` listening comprehension. the present study investigated ways in which learners` background knowledge could be activated in order to enhance their l2 listening comprehension by limiting the number of possible text interpretations prior to listening. the experiments conducted in this study examined the effect of prior knowledge and vocabulary teaching on iranian efl learners listening comprehension. the current study has two purposes: one is to investigate the effect of background knowledge on the second language listening comprehension of iranian intermediates and the other is to determine whether second language is facilitated by the introduction of unknown vocabularies in the form of prelistening activities. to conduct the study different instruments such as listening proficiency test and four listening tests such as pre and posttests were used and various statistical processes and techniques including paired-sample t-test, and analysis of variance (anova) were used. the findings of this study supported all three hypotheses tested. differences were found between the means of preteaching vocabulary variable, the background knowledge activation variable, and mean difference between these two strategies variable. subjects scored higher when the unknown words were taught in advance. likewise, subjects scored higher when they were asked some relevant questions about the topic than on those without them. there was, in addition, a significant difference between the means of preteaching vocabulary strategy and background knowledge activation strategy. in fact, preteaching vocabulary had a better effect in enhancing the students’ listening comprehension, in comparison to background knowledge activation strategy.

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد تهران مرکزی - دانشکده زبانهای خارجی 1390

this thesis attempts to investigate the effects of prelistening activities on enhancing iranian efl learners` listening comprehension. the present study investigated ways in which learners` background knowledge could be activated in order to enhance their l2 listening comprehension by limiting the number of possible text interpretations prior to listening. the experiments conducted in this stud...

Journal: :Structure 2016
Fiona J Sorrell Marta Szklarz Kamal R Abdul Azeez Jon M Elkins Stefan Knapp

The highly diverse Numb-associated kinase (NAK) family has been linked to broad cellular functions including receptor-mediated endocytosis, Notch pathway modulation, osteoblast differentiation, and dendrite morphogenesis. Consequently, NAK kinases play a key role in a diverse range of diseases from Parkinson's and prostate cancer to HIV. Due to the plasticity of this kinase family, NAK kinases ...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد تهران مرکزی - دانشکده ادبیات و زبانهای خارجی 1390

the present paper offers a postcolonial reading of two of the best novels by v. s. naipaul – half a life and the mimic men – in five chapters. the focus of this research is on different notions of postcolonial criticism and their application on the two novels as discussed from homi bhabha’s and frantz fanons points of view. having introduced the life and literary career of v. s. naipaul in th...

Journal: :Neuron 2011
Wei-Kang Yang Yu-Huei Peng Hsun Li Hsiu-Chen Lin Yu-Ching Lin Tzu-Ting Lai Hsien Suo Chien-Hsiang Wang Wei-Hsiang Lin Chan-Yen Ou Xin Zhou Haiwei Pi Henry C. Chang Cheng-Ting Chien

VIDEO ABSTRACT During development, dendrites arborize in a field several hundred folds of their soma size, a process regulated by intrinsic transcription program and cell adhesion molecule (CAM)-mediated interaction. However, underlying cellular machineries that govern distal higher-order dendrite extension remain largely unknown. Here, we show that Nak, a clathrin adaptor-associated kinase, pr...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2015
Joshua B Brettmann Darya Urusova Marco Tonelli Jonathan R Silva Katherine A Henzler-Wildman

Flux-dependent inactivation that arises from functional coupling between the inner gate and the selectivity filter is widespread in ion channels. The structural basis of this coupling has only been well characterized in KcsA. Here we present NMR data demonstrating structural and dynamic coupling between the selectivity filter and intracellular constriction point in the bacterial nonselective ca...

پایان نامه :دانشگاه تربیت معلم - تهران - دانشکده ادبیات و علوم انسانی 1391

the present study aimed at exploring cognitions of iranian english teachers within the context of english for academic purposes (eap). to this end, the cognitions of two groups of eap teachers with respect to their pedagogical content knowledge (pck) and their sense of professional identity (pi) were probed. two language teachers and two content instructors who had at least five years of eap te...

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