نتایج جستجو برای: framingham risk score

تعداد نتایج: 1121300  

Journal: :Circulation 2009
Julian P J Halcox Ann E Donald Elizabeth Ellins Daniel R Witte Martin J Shipley Eric J Brunner Michael G Marmot John E Deanfield

BACKGROUND Endothelial dysfunction develops early and has been shown to predict the development of clinical complications of atherosclerosis. However, the relationship between early endothelial dysfunction and the progression of arterial disease in the general population is unknown. We investigated endothelial dysfunction, risk factors, and progression of carotid intima-media thickness (cIMT) i...

Journal: :The American journal of cardiology 2012
Cynthia S Crowson Eric L Matteson Veronique L Roger Terry M Therneau Sherine E Gabriel

Patients with rheumatoid arthritis (RA) have an excess burden of cardiovascular (CV) disease (CVD). CV risk scores for the general population may not accurately predict CV risk for patients with RA. A population-based inception cohort of patients who fulfilled 1987 American College of Rheumatology criteria for RA from 1988 to 2007 was followed until death, migration, or December 31, 2008. CV ri...

Journal: :European heart journal 2003
Charles H Hennekens Ralph B D'Agostino

In their thoughtful and provocative article ‘Are the Framingham and PROCAM coronary heart disease risk functions applicable to different European populations? The PRIME Study’, Drs Empana and colleagues astutely conclude that the answer is neither simple nor straightforward. On the one hand, they conclude that the Framingham (from the United States) and PROCAM (from Germany) risk functions over...

Journal: :Stroke 2008
Patrizio Prati Alberto Tosetto Diego Vanuzzo Giovanni Bader Marco Casaroli Luigi Canciani Sergio Castellani Pierre-Jean Touboul

BACKGROUND AND PURPOSE The clinical usefulness of noninvasive measurement of carotid intima media thickness and plaque visualization in the general population is still uncertain. METHODS We evaluated the age-specific incidence rates of cerebrovascular events in a cohort of 1348 subjects randomly taken from the census list of San Daniele Township and followed for a mean period of 12.7 years. T...

Journal: :Stroke 2014
Carla A Ibrahim-Verbaas Myriam Fornage Joshua C Bis Seung Hoan Choi Bruce M Psaty James B Meigs Madhu Rao Mike Nalls Joao D Fontes Christopher J O'Donnell Sekar Kathiresan Georg B Ehret Caroline S Fox Rainer Malik Martin Dichgans Helena Schmidt Jari Lahti Susan R Heckbert Thomas Lumley Kenneth Rice Jerome I Rotter Kent D Taylor Aaron R Folsom Eric Boerwinkle Wayne D Rosamond Eyal Shahar Rebecca F Gottesman Peter J Koudstaal Najaf Amin Renske G Wieberdink Abbas Dehghan Albert Hofman André G Uitterlinden Anita L Destefano Stephanie Debette Luting Xue Alexa Beiser Philip A Wolf Charles Decarli M Arfan Ikram Sudha Seshadri Thomas H Mosley W T Longstreth Cornelia M van Duijn Lenore J Launer

BACKGROUND AND PURPOSE Beyond the Framingham Stroke Risk Score, prediction of future stroke may improve with a genetic risk score (GRS) based on single-nucleotide polymorphisms associated with stroke and its risk factors. METHODS The study includes 4 population-based cohorts with 2047 first incident strokes from 22,720 initially stroke-free European origin participants aged ≥55 years, who wer...

2017
Xiao-Hua Zhou Xiaonan Wang Ashlee Duncan Guizhou Hu Jiayin Zheng

BACKGROUND Framingham Stroke Risk Score (FSRS) is the most well-regarded risk appraisal tools for evaluating an individual's absolute risk on stroke onset. However, several widely accepted risk factors for stroke were not included in the original Framingham model. This study proposed a new model which combines an existing risk models with new risk factors using synthesis analysis, and applied i...

2010
Todd J. Anderson Marinda Fung

Background—Biomarkers of atherosclerosis may refine clinical decision making in individuals at risk of cardiovascular disease. The purpose of the study was to determine the prognostic significance of endothelial function and other vascular markers in apparently healthy men. Methods and Results—The cohort consisted of 1574 men (age, 49.4 years) free of vascular disease. Measurements included flo...

Journal: :Circulation 2011
Todd J Anderson Francois Charbonneau Lawrence M Title Jean Buithieu M Sarah Rose Heather Conradson Kathy Hildebrand Marinda Fung Subodh Verma Eva M Lonn

BACKGROUND Biomarkers of atherosclerosis may refine clinical decision making in individuals at risk of cardiovascular disease. The purpose of the study was to determine the prognostic significance of endothelial function and other vascular markers in apparently healthy men. METHODS AND RESULTS The cohort consisted of 1574 men (age, 49.4 years) free of vascular disease. Measurements included f...

2017
Joseph F. Polak Moyses Szklo Daniel H. O'Leary

BACKGROUND Common carotid artery and internal carotid artery intima-media thicknesses (IMT) are associated with coronary heart disease (CHD) and increase with age. Using age, sex, and race/ethnicity IMT percentiles may improve CHD prediction when added to Framingham risk factors and coronary artery calcium score. We study these possibilities in the Multi-Ethnic Study of Atherosclerosis (MESA), ...

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