Formobactin, a new free radical scavenger, was isolated from the culture of Nocardia sp. strain ND20. The structure of formobactin was determined to be a member of the nocobactin group antibiotics. Formobactin inhibited lipid peroxidation in rat brain homogenate. Formobactin also showed the activity to suppress L-glutamate toxicity in neuronal hybridoma N18-RE-105 cells.

The flower pigment of Calliandria suninamensis is used folklorically as a colorant and a dye. The crude powdered sample and methanolic extract of the plant were subjected to phytochemical, proximate analysis and antioxidant activities. Parameters like moisture content, ash values and extractive values were determined. The methanolic extract was evaluated for its antioxidant/free radical scaveng...

Promethazine is known to have protective activity in relation to CCl4-induced liver necrosis. This hepatoprotective property has been investigated with regard to the free radical scavenging and antioxidant properties of promethazine using isolated hepatocytes and microsomal suspensions. CCl4 is activated in both systems to free radical metabolites that bind covalently to lipid and protein, and ...

antibacterial, antifungal and antioxidant activities of methanolic crude extracts from aerial parts of four arnebia species namely arnebia fimbriopetala, arnebia linearifolia, arnebia garandiflora, arnebia tubata were screened. total phenolic contents were determined by folin-ciocalteu procedure and ranged from 2.2 ± 0.13 (a. fimbriopetala) to 1.6 ± 1.0 mg (arnebia tubata) gallic acid µmol equi...

Purwoceng (Pimpinella alpina Molk) is a traditional medicinal plant used for its aphrodisiac values. This plant was originated Dieng Plateu, Central Java, Indonesia. Purwoceng has been reported to contain steroid, flavonoids, glycoside, saponins, tannins, and phenolic. Based on secondary metabolite compounds of Purwoceng herbs, a research need to be done to determine the other potential free ra...

RATIONALE Sepsis produces significant mitochondrial and contractile dysfunction in the heart, but the role of superoxide-derived free radicals in the genesis of these abnormalities is not completely understood. OBJECTIVES The study was designed to test the hypothesis that superoxide scavenger administration prevents endotoxin-induced cardiac mitochondrial and contractile dysfunction. METHOD...

background: thymus daenensis celak. is one of the medicinal plants which cultivated in iran. this plant involve high amount of polyphenols including thymol and carvacrol, which were reported to possess the high antioxidant activity. objective: antioxidative activity (aoa) and chemical constituents of thymus daenensis essential oil (tdeo) were examined. also, the effect of thermal treatments (80...

background: in recent years, natural products, especially natural antioxidants, play an important role in various fields. in fact, lippia citriodora is one of the medicinal plants which is cultivated in iran and it may be has potential antioxidant activity. objective: the chemical composition of lippia citriodora essential oil (lceo) has been determined. the total phenolic content and antioxida...