BACKGROUND Skin basal and squamous cell carcinomas together account for over half of all newly diagnosed cancer cases. Frozen section control of surgical margins is often required in the head and neck region. A paraffin permanent section does not always confirm the results of a frozen section. OBJECTIVES To test the diagnostic accuracy of frozen section histopathological analysis in determini...

BACKGROUND The value of frozen sections in the intraoperative examination of sentinel nodes (SN) remains controversial. Accurate frozen sections will spare those patients with node metastasis from a second procedure to complete the axillary dissection. We examined our own experience with intraoperative examination of SN. STUDY DESIGN Between January 1, 2006, and December 31, 2006, we performe...

The elasticity of biological tissues is one the physical characteristics and has attracted attention as a clinical diagnostic parameter. can be determined on microscopic scale with speed sound (SoS) measurements using acoustic microscopy. In SoS measurements, thin-sliced section attached to glass slide in same manner light specimen. There are two main methods for preparing thin sections: paraff...

BACKGROUND Acute rejection may be suspected in heart transplant recipients in the setting of new onset of clinical symptoms or alterations in cardiac function. Immediate diagnosis may be obtained by performing a frozen section on endomyocardial biopsy (EMB) specimens. However, little is known about the indications for, and the diagnostic reliability of, this procedure. METHODS AND RESULTS EMB...

Imprints prepared from fresh surgical specimens give excellent cytological clarity. Used intraoperatively, the imprint method can provide valuable information when frozen-section interpretation is equivocal. However, cytologically well-differentiated tumours and tumours with a dense fibrous stroma, constituting 6% of the cases in the present series, cannot be diagnosed by this method. To increa...

Intra-operative frozen section plays an important role in the management of surgical patients and yet it must be used prudently to avoid the indiscriminate usage of this important technique. As it is subjected to many limitations in comparison to the paraffin embedded tissue sections, this review aims to highlight the important concepts and principle of intra-operative frozen section consultati...

Background: Intra-operative frozen section plays an important role in the management of surgical patients but yet it must be used prudently to avoid the indiscriminate usage of this technique. As it is subjected to many limitations in comparison to the paraffin embedded sections, this study aims to highlight the important concepts and principles of intraoperative frozen section consultation as ...

Tumour imprints were made from 311 breast tumours at the time of frozen section. Rapid and permanent staining methods were employed and the accuracy of diagnosis was compared with that obtained from frozen and paraffin sections. Two false positives (0.65%) and 16 false negatives (5.15%) were found in the imprint group compared with no false positives and five false negatives (1.6%) in the froze...

Background. The feasibility and accuracy of immunohistochemistry (IHC) on frozen sections, when assessing sentinel node (SN) status intraoperatively in breast cancer, is a matter of continuing discussion. In this study, we compared a center using IHC on frozen section with a center not using this method with focus on intraoperative diagnostic values. Material and Methods. Results from 336 patie...