BACKGROUND Feline calicivirus (FCV) is a common cause of upper respiratory tract disease in cats worldwide. Its characteristically high mutation rate leads to escape from the humoral immune response induced by natural infection and/or vaccination and consequently vaccines are not always effective against field isolates. Thus, there is a need to continuously investigate the ability of FCV vaccin...

A serosurvey of feline herpesvirus type 1 (FHV-1), feline calicivirus (FCV), and feline parvovirus (FPV) in cats from Ho Chi Minh City area in southern Vietnam was conducted in December 1998, and we compared the results with our previous results in northern Vietnam (Hanoi area). The positive rate of FHV and FCV in domestic cats were 44% and 74%, respectively. They were rather higher than those ...

Feline Caliciviral infection is typically associated with mild depression, sneezing, ocular and nasal discharges, and often mouth ulceration. However, isolates vary in their pathogenicity. Some isolates reproducibly cause a more severe syndrome; some induce oral or nasal ulceration alone; some induce an interstitial pneumonia and some appear to be apathogenic[ 1-31. Infection with feline calici...

Feline Viral Upper Respiratory Tract Disease Feline viral upper respiratory tract disease is typified by signs of rhinosinusitis, conjunctivitis, lacrimation, salivation, and/or oral ulcerations. The principal causative agents are feline herpesvirus type 1 (FHV-1 ) and feline calicivirus (FCV). These viruses are host-specific and pose no known human risk. Other infectious agents (e.g. Bordetell...

Feline Calicivirus (FCV) infection results in the inhibition of host protein synthesis, known as "shut-off". However, the precise mechanism of shut-off remains unknown. Here, we found that the FCV strain 2280 proteinase-polymerase (PP) protein can suppress luciferase reporter gene expression driven by endogenous and exogenous promoters. Furthermore, we found that the N-terminal 263 aa of PP (PP...

BACKGROUND AND OBJECTIVES Feline herpesvirus-1, feline calicivirus and Chlamydophila felis are the main causes of feline upper respiratory tract disease. This study was conducted to identify of FeHV-1, FCV and C. felis infections in domestic cat population and also to estimate the prevalence of each specific infection in Iran. MATERIALS AND METHODS The ocular conjunctiva and oropharyngeal spe...

A common feature of caliciviruses is the proteolytic processing of the viral polyprotein catalyzed by the viral 3C-like protease encoded in open reading frame 1 (ORF1). Here we report the identification and structural characterization of the protease domains and amino acid residues in sapovirus (SaV) and feline calicivirus (FCV). The in vitro expression and processing of a panel of truncated OR...

The control of outbreaks of calicivirus infection in high-density, high-throughput populations is a challenge to both human and veterinary medicine. In such populations, the prevalence of infection is, in part, dependent on the levels of biosecurity and how this affects virus transmission. Here we show how longitudinal analysis of feline calicivirus (FCV) infection in an animal rescue shelter c...

BACKGROUND Feline calicivirus (FCV) is a common virus, found worldwide, mainly responsible for chronic ulceroproliferative faucitis and periodontitis. This virus has a high mutation rate, leading to the presence of numerous FCV strains in the field. The objectives of this study was to evaluate and compare the efficacy of two vaccines (Leucofeligen™ FeLV/RCP and Purevax™ RCP FeLV), which differ ...

There are a few fundamental pointing-based user interface techniques for performing selections in 3D environments. One of these techniques is ray pointing, which makes selections by determining intersections of objects along a single ray cast from the user. This technique is susceptible to inaccuracy of the user interface tracking technology and user noise (e.g., jittery hand, see actual viewin...