metal nanoshells consists of a dielectric core surrounded by a thin noble metal shell, possess unique optical properties that render nanoshells attractive for use in different technologies. this paper reports a facile method for growth of small gold nanoparticles on the functionalized surface of larger silica nanoparticles. mono-dispersed silica particles and gold nanoparticles were prepared by...

Non-activated 2-(4-chloro-2-cyano-2-phenylbutyl)aziridines were used as building blocks for the stereoselective synthesis of novel cis-2-cyanomethyl-4-phenylpiperidines via a microwave-assisted aziridine to piperidine ring expansion followed by a radical-induced nitrile translocation through initial formation and subsequent cleavage of intermediate bicyclic iminyl radicals. Furthermore, these 2...

Eight novel 1-(substituted acetyl)-4-(10-bromo-8-chloro-5,6-dihydro-11H-benzo[5,6] cyclohepta [1,2-b] pyridine-11-ylidene)piperidines were designed by incorporating zinc binding groups to enhance activity. The designed molecules were synthesized and were evaluated for antitumor activity in vitro in five cell lines and for farnesyl protein transferase inhibition. Test compounds (6a-h) exhibited ...

objective(s): first principles calculations were performed to study four multiple sclerosis drugs namely, ampyra, fingolimod, mitoxantrone and eliprodil in gas and liquid phases using density functional theory (dft). computational chemistry simulations were carried out to compare calculated quantum chemical parameters for ampyra, fingolimod, mitoxantrone and eliprodil. materials and methods: al...

reducing co2 emission and lowering the concentration of greenhouse gases in the atmosphere has quickly become one of the most urgent environmental issues. while a variety of technologies and methods have been developed, the separation of co2 from gas streams is still a critical issue. apart from establishing new techniques, the exploration of membrane materials with high separation performance ...

In this paper functionalized multiwall carbon nanotubes (FMWCNT) were modified using doxycycline, containing reactable nitrogen, which can attach chemically to functionalized MWCNT. The synthesized nano compounds were characterized by Fourier transform infrared spectroscopy (FT-IR) and Raman spectroscopy. These spectrums proved the existence of nitrogen atoms of amide functional groups. The mor...