trichophyton rubrum is an anthropophilic fungus causing up to 90% of chronic cases of dermatophytosis. several properties of this fungus have been investigated so far. however, a few studies were carried out in the field of molecular biology of this fungus. in the present study, we tried to identify the subunit g of its vacuolar atpase (v-atpase). pairs of 21 nt primers were designed from highl...

Background: Several studies reported the clinical features of IgE-mediated hypersensitivity after ingestion of melon. Melon allergy is a common IgE-mediated fruit allergy in Iran. This prompted us to investigate immunochemical and molecular properties of the major allergen in melon fruit, to compare the IgE-binding capacity of the natural protein with the recombinant allergen, and to determine ...

The efficacy of allergen immunotherapy for the treatment of allergic rhinoconjunctivitis with or without seasonal bronchial asthma and anaphylaxis caused by the sting of the hymenoptera class of insects has been clearly demonstrated in numerous well-designed, placebo-controlled trials. Immunotherapy whether by subcutaneous injection of allergen extract or by oral/sublingual routes modifies peri...

specific local immunotherapy has been recently introduced as an alternative to classic subcutaneous immunotherapy in treatment of allergic rhinitis. in this study, the effects of sublingual immunotherapy (slit) on symptoms and medication score and skin prick test evaluation of patients with allergic rhinitis were investigated. in this placebo controlled trial, twenty four patients aged 5-18 yea...

Fusarium species are among airborne fungi and recognized as causative agents of human atopic disorders. However, Fusarium allergens have not been well characterized and the lack of information limits clinical diagnosis and treatment of fungal allergy. The purpose of this study is to identify and characterize important allergens of F. proliferatum. IgE-reacting F. proliferatum components were id...

background : cockroaches have been recognized as a powerful indoor allergen. cockroach allergy can be a major factor in seri­ous asthma and nasal allergy. bioinformatics tools have been developed to identify potential allergens. the present study was conducted to identify potential allergens in  periplaneta americana (linnaeus). methods : the study focused on the identification of potential all...

allergy to prosopis juliflora (mesquite) pollen is one of the common causes of respiratory allergy in tropical countries. mesquite is widely used as street trees in towns and ornamental shade trees in parks and gardens throughout arid and semiarid regions of iran. the inhalation of mesquite pollen and several species of amaranthus/chenopodiaceae family is the most important cause of allergic re...

Today a large part of the European population is exposed to levels air pollution exceeding standards recommended by World Health Organization. Moreover, and seasonal emission allergenic pollen are progressively affecting human health can cause severe allergic reactions, particularly when combines with allergen peaks. Unlike atmospheric pollutants anthropogenic origin, sources have pulsating tre...

Very little is known about the impact of climate change on fungi and especially on spore production. Fungal spores can be allergenic, thus being important for human health. The aim of this study was to investigate how climate change influences the responsive ability of fungi by simulating differing environmental regimes. Fungal species with high spore allergenic potential and atmospheric abunda...

Background: Epidemiologic studies have demonstrated an association between indoor fungal growth and respiratory symptoms. However, in only a few studies was fungal exposure actually measured. Objective: The purpose of this study was to evaluate the measurement by enzyme immunoassay of extracellular polysaccharides of Aspergillus and Penicillium species (EPS-Asp/Pen) in house dust as a marker fo...