This article reviews routine quality-control (QC) procedures for current nuclear medicine instrumentation, including the survey meter, dose calibrator, well counter, intraoperative probe, organ ("thyroid") uptake probe, gamma-camera, SPECT and SPECT/CT scanner, and PET and PET/CT scanner. It should be particularly useful for residents, fellows, and other trainees in nuclear medicine, nuclear ca...

A cDNA clone corresponding to a novel cGMP phosphodiesterase inhibitory subunit (PDE gamma) was isolated from a bovine retinal cDNA library using a rod PDE gamma cDNA as a probe under conditions of reduced stringency. This new clone encodes an 83-amino acid protein approximately 80% identical to rod PDE gamma. The transcript for this protein is retina specific and 940 base pairs in length. Sout...

We show that, if the long GRBs are produced by the collapse of massive stars, GRBs and their afterglows may provide a powerful probe of cosmology and the early universe.

OBJECTIVES The pioneering performance of gamma probe-assisted surgery (GPAS) for brain tumors, aiming not only an improvement of tumor detection, but mainly assurance of its complete removal and the study of the usual distribution of the 99mTc-MIBI in the brain SPECT of normal individuals. METHOD Patient's informed consent and demonstration of the tumor by the preoperative MIBI SPECT were the...

In complex (robot-assisted) laparoscopic radioguided surgery procedures, or when low activity lesions are located nearby a high activity background, the limited maneuverability of a laparoscopic gamma probe (LGP; 4 degrees of freedom (DOF)) may hinder lesion identification. We investigated a drop-in gamma probe (DIGP) technology to be inserted via a trocar, after which the laparoscopic surgical...

A novel dual-modality molecular probe composed of biocompatible Fe(3)O(4) nanocrystal, monoclonal antibody and radionuclide was designed and prepared. All functional components in the dual-modality molecular probe, i.e., Fe(3)O(4), PEG, mAb 3H11 and (125)I, were chemically bonded together for forming a stable molecular probe. Systematic in vitro experiments were carried out for evaluating the b...

We used local field potentials (LFPs) and spikes to investigate representations of visual space in prefrontal cortex and the dynamics of those representations during eye movements. Spatial information contained in LFPs of the frontal eye field (FEF) was differentially distributed across frequencies, with a majority of that information being carried in alpha and high-gamma bands and minimal sign...

magnetic force microscope ( mfm ) is a powerful technique for mapping the magnetic force gradient above the sample surface. herein, single-wall carbon nanotubes (swcnt) were used to fabricate mfm probe by dielectrophoresis method which is a reproducible and cost-effective technique. the effect of induced voltage on the deposition manner of carbon nanotubes (cnt) on the atomic force microscope (...

In light of the recent finding of the narrow clustering of the geometrically-corrected gamma-ray energies emitted by Gamma Ray Bursts (GRBs), we investigate the possibility to use these sources as standard candles to probe cosmological parameters such as the matter density Ωm and the cosmological constant energy density ΩΛ. By simulating different samples of gamma-ray bursts, based on recent ob...

where k indexes experimental replicates, i indexes the probe positions, j indexes the binding positions, andN ( jPj aji jjsjbj; i) represents the probability density function of a Gaussian distribution with mean Pj aji jjsjbj and variance i. We assign prior distributions on the binding event bj and the binding strength sj: p(bjj j) = bj j (1 j)1 bj (3) p0(sj) = Gamma(sjjc0; d0) (4) where Gamma(...