The methanol extract of the leaves of Garcinia nervosa var. pubescens King, which showed strong inhibitory effects on platelet-activating factor (PAF) receptor binding, was subjected to bioassay-guided isolation to obtain a new biflavonoid, II-3,I-5, II-5,II-7,I-4',II-4'-hexahydroxy-(I-3,II-8)-flavonylflavanonol together with two known flavonoids, 6-methyl-4'-methoxyflavone and acacetin. The st...

OBJECTIVES Over the past years, there has been a growing number of knee osteoarthritis (KOA) patients who are not willing to comply with long-term non-steroidal anti-inflammatory drugs (NSAID) treatment and wish to use herbal anti- rheumatic medicine. This study assessed the clinical effects of Garcinia kola (GK) in KOA patients. PATIENTS AND METHODS Prospective randomized, placebo controlled...

the aim of the study was to investigate the improving effect of garcinia cambogia extract on performance metrics, and serum non-esterified fatty acids (nefa) and c-reactive protein (crp) levels in rats fed with atherogenic diet. thirty, one-year-old, female sprague-dawley rats were randomly assigned to threeexperimental groups of ten animals each. control group was fed with basal diet (2% liqui...

the aim of the study was to investigate the preventive effects of dietary garcinia cambogia extract onlipid metabolism and serum activities of alanine aminotransferase (alt), aspartate aminotransferase (ast)and gamma-glutamyle transferase (ggt) in rats fed high-lipid diet. thirty female, one-year-old sprague-dawley rats were used and separated into three equal groups. group 1 (control group) wa...

background: garcinia kola seed is consumed indiscriminately in nigeria without recourse to its potential toxicity. therefore, this study was aimed at assessing the toxicity of the aqueous extract of g. kola seeds on selected tissues of male rats.  methods: thirty male rats (215.00 ± 18.58 g) were assigned into four groups: a, b, c and d which received 0.5 ml of distilled water, 25, 50 and 100 m...

BACKGROUND Resistance of antimalarial drugs to Plasmodium falciparum has become a major concern in malaria eradication. Although it is also affected by several socioeconomic factors, a new antiplasmodial agent is needed for a global malaria control program. OBJECTIVE In this study, we attempted to uncover the antiplasmodial properties of Garcinia celebica, an Indonesian medicinal plant, along...

5,9,11-Trihydroxy-2,2-dimethyl-10-(3′-methyl-2′-butenyl)-3-(2”-methyl-3”-butenyl)pyrano[2,3-a]xanthen-12(2H)-one (1) was isolated from the stem bark of Calophyllum pseudomole. The structure of 1 was established by spectroscopic analysis which included UV, IR, HRESIMS and NMR experiments.

The aim of the study was to investigate the effect of the antiobesity agent Garcinia cambogia extract, on serum lipoprotein (a), apolipoproteins A1 (apo A1) and B (apo B), and total cholesterol levels in atherogenic diet fed rats. Thirty female, one year old Sprague-Dawley rats were separated to three equal groups. Group 1 (control group) was fed basal diet (2% liquid vegetable oil, 0% choleste...