نتایج جستجو برای: gastroesophageal junction

تعداد نتایج: 63780  

2013
Guichao Li Zhen Zhang Xuejun Ma Ji Zhu Gang Cai

BACKGROUND Due to low tolerance to chemotherapy, the maximum number of cycles of postoperative adjuvant chemotherapy is 4 in adjuvant gastric clinical trials. The aim of this study is to retrospectively evaluate the safety and efficacy of adjuvant epirubicin-based triplet chemotherapy and radiotherapy in the treatment of resected locally advanced stomach or gastroesophageal junction adenocarcin...

Journal: :International journal of cancer 2016
Jennifer Drahos Qian Xiao Harvey A Risch Neal D Freedman Christian C Abnet Lesley A Anderson Leslie Bernstein Linda Brown Wong-Ho Chow Marilie D Gammon Farin Kamangar Linda M Liao Liam J Murray Mary H Ward Weimin Ye Anna H Wu Thomas L Vaughan David C Whiteman Michael B Cook

Esophageal (EA) and esophagogastric junction (EGJA) adenocarcinoma have been steadily increasing in frequency in younger people; however, the etiology of these cancers is poorly understood. We therefore investigated associations of body mass index (BMI), cigarette smoking, alcohol consumption, gastroesophageal reflux and use of nonsteroidal anti-inflammatory drugs (NSAIDs) in relation to age-sp...

2013
Tanya Dam Aftab Mahmood Kenneth Linville Michael Bailey Salim Surani

Gastroesophageal adenocarcinoma is a malignant type of cancer, which can metastasize to multiple organs. However, there have not been many case reports in the literature pertaining the relationship of gastroesophageal adenocarcinoma and carcinomatous meningitis. In this case, a 65-year-old African American male with a history of dysphagia was initially diagnosed with adenocarcinoma at gastroeso...

Journal: :American journal of epidemiology 2011
Catherine M Olsen Nirmala Pandeya Adèle C Green Penelope M Webb David C Whiteman

Obesity, gastroesophageal reflux, and smoking have repeatedly been shown to be important and independent risk factors for adenocarcinoma of the esophagus (EAC) and of the gastroesophageal junction (GEJAC). There have been few attempts, however, to quantify the proportion of disease associated with these potentially modifiable factors. The authors have estimated the population attributable fract...

Journal: :Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2005
C L A Barbieri L E A Troncon J R L Herculano L R O Aprile R O Dantas

Patients with gastroesophageal reflux disease may have disturbances of gastric motility, which could play a role in the pathophysiology of the disease. Recent studies have suggested that the gastric region just below the gastroesophageal junction may have a distinct physiological behavior. We determined whether patients with gastroesophageal reflux disease have abnormal residence of food in the...

2011
Catherine M. Olsen Nirmala Pandeya Adèle C. Green Penelope M. Webb

Obesity, gastroesophageal reflux, and smoking have repeatedly been shown to be important and independent risk factors for adenocarcinoma of the esophagus (EAC) and of the gastroesophageal junction (GEJAC). There have been few attempts, however, to quantify the proportion of disease associated with these potentially modifiable factors. The authors have estimated the population attributable fract...

Journal: :Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 2010
J C Alvaro-Villegas S Sobrino-Cossío A Hernández-Guerrero J O Alonso-Lárraga J G de-la-Mora-Levy A Molina-Cruz H R Domínguez-Malagón J J Herrera-Esquivel

BACKGROUND Dilatation of the intercellular spaces by electron microscopy has been considered as an early morphological marker of tissue injury in gastroesophageal reflux disease. The degree of dilatation in Barret's esophagus in currently unknown. OBJECTIVES To determine the frequency of dilated intervellular spaces in Barrett's esophagus. MATERIAL AND METHODS Cross-sectional and prospectiv...

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