In this paper, different formulation types of microparticulate systems such as beads, microbeads, microspheres and microsponges using to special attention chitosan, alginate and eudragit RS 100 are reviewed. Chitosan and alginates are natural, anionic or cationic, biocompatible, biodegredable and non-toxic polymers. They have excellent potential for pharmaceutical and biopharmaceutical applicat...

In the present study an attempt was made to prepare alginate floating microparticles by ionotropic gelation method with calcium carbonate (CaCO3) 1% w/v in gelation medium used as gas-forming agent for oral delivery of Ofloxacin. Chitosan was used to enhance the drug encapsulation efficiency. Various physiochemical properties such as particle size, shape, in vitro buoyancy and drug release was ...