Currently, COVID-19 is spreading in a large scale while no efficient vaccine has been produced. A high-effective drug for very necessary now. We established satisfied quantitative structure–activity relationship model by gene expression programming to predict the IC50 value of natural compounds. total 27 products were optimized heuristic method CODESSA program build liner model. Based on it, on...

Turbulence in two-phase flows drives many important natural and engineering processes, from geophysical to nuclear power generation. Strong interphase coupling between the carrier fluid disperse phase precludes use of classical turbulence models developed for single-phase flows. In recent years, there has been an explosion machine learning techniques closure modeling, though rely on augmenting ...

objective: today, aids is considered as a global problem and many efforts to generate an effective vaccine against this disease have been made, but remain inconclusive. dna vaccines are a member of the new generation of vaccines that can efficiently stimulate the immune system. however, recent findings indicate low immunogenicity for these vaccines and it is believed that these types of vaccine...

multiple sclerosis (ms) is an inflammatory, multifocal, immune-mediated disease of the central nervous system that women are at a higher risk to acquire than men. myxovirus resistance protein a (mxa) is used as a predictive marker of bioactivity of interferon-beta (ifn-β) therapy in ms patients. this study was undertaken in west of iran to investigate gender differences in the expression level ...