نتایج جستجو برای: gene products
تعداد نتایج: 1396770 فیلتر نتایج به سال:
miRNAs are a well-established RNA phenomenon. Previously, we analyzed the involvement of HIV-1 protein Tat in cellular gene networks and aspects of its interaction with miRNAs [1]. Here we mention an additional HIV-1 protein, HIV-1 viral protein R (Vpr) that interacts with miRNAs and it is involved in gene expression networks. The manipulation of miRNA expression is anticipated to become import...
Background: Species identification in commercially processed food and feed products is one of the important issues. This study was conducted to develop a genetic method for the detection of pig and cattle species in processed food and feed products using newly designed species-specific primers targeting mitochondrial 12S rRNA gene fragments. Methods: Two sets of specific primers were designed ...
Introduction: Today, treatment with CAR-T cells is accepted as an effective treatment for blood malignancies. CAR-T cells are autologous T cells that are engineered by gene transfer techniques to express a chimeric antigen receptor (CAR). Despite the promising results and the approval of six CAR-T cell products; these products have not yet been approved for solid tumors. In addition, the high c...
background: trichomonas vaginalis causes trichomoniasis and metronidazole is its chosen drug for treatment. ferredoxin has role in electron transport and carbohydrate metabolism and the conversion of an inactive form of metronidazole (co) to its active form (cpr). ferredoxin gene mutations reduce gene expression and increase its resistance to metronidazole. in this study, the frequency of ferre...
background type 1 diabetes mellitus is one of the metabolic diseases that cause insulin-producing pancreatic ß cells be destroyed by immune system self-reactive t cells. recently, new treatment methods have been developed including use of the stem cells, ß islet cells transplantation and gene therapy by viral and non-viral gene constructs. objectives the aim of this project was preparing the n...
Introduction: Breast cancer is one of the leading causes of cancer death in women. Variations in the BRCA1, BRCA2, CDH1, STK11 and TP53 genes increase the risk of developing breast cancer. In addition to specific genetic changes, environmental factors may influence an individual’s risk of developing breast cancer. Lead is one of the most dangerous chemicals in the air as well as many products,...
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