The chemoresistance of non-small cell lung cancer (NSCLC) that occurs in docetaxel (DOC) chemotherapy substantially decreases the survival of patients. To overcome DOC-induced chemoresistance, we established DOC-selected A549 lung cancer sublines (A549/D16 and A549/D32) and revealed that both sublines were cross-resistant to vincristine (VCR) and doxorubicin (DXR). Notably, both sublines were m...

Abstract Aim This audit reviewed management practice of patients admitted to Gozo General Hospital with a head injury, see whether guidelines are being followed. Method All GGH injury over twelve-month period (December 2019 – November 2020) were retrospectively reviewed. We used National Institute for Health Care Excellence (NICE) clinical guidance 176 as the standard compare to. Results 61 pat...

Introduction: Acute kidney failure (AKF) / injury (AKI) Is defined as sudden deterioration in function that leads to the accumulation of nitrogenous waste products (e.g.urea) and alters regulation extra cellular fluid volume, electrolyte acid-base homeostasis. Renal dysfunction due acute is common high-risk newborn babies its incidence varies depending upon criteria used for diagnosis. Material...

Suicidal death is nothing but ending one’s own life, which the most daunting human tragedies and a seriouspublic health problem. As for NCRB suicide rate has increased from 6.2% (2020) to 7.2% (2021).This study takes100 cases retrospectively duration of 6 months. All suicidal deaths postmortem examinations are donein reproductive age group females April 2022 September 2022. Those occurred on sp...

Abstract. The security of lattice-based cryptosystems such as NTRU, GGH and Ajtai-Dwork essentially relies upon the intractability of computing a shortest non-zero lattice vector and a closest lattice vector to a given target vector in high dimensions. The best algorithms for these tasks are due to Kannan, and, though remarkably simple, their complexity estimates have not been improved since ov...

NTRU public key cryptosystem is well studied lattice-based Cryptosystem along with Ajtai-Dwork and GGH systems. Underlying NTRU is a hard mathematical problem of finding short vectors in a certain lattice. (Shamir 1997) presented a lattice-based attack by which he could find the original secret key or alternate key. Shamir concluded if one designs a variant of NTRU where the calculations involv...