Introduction: Head injury is one of the most critical conditions and has a serious neurological outcome if not treated promptly. Effective initial assessment timely intervention ensures favourable outcome. To achieve this, many scoring systems have been devised over years which Glasgow coma scale (GCS) widely used but it does few drawbacks. A newer scale, FOUR score (Full Outline UnResponsivene...

BACKGROUND AND PURPOSE The purpose of this study was to investigate the relationship between cerebrovascular autoregulation and outcome after aneurysmal subarachnoid hemorrhage. METHODS In a prospective observational study, 80 patients after severe subarachnoid hemorrhage were continuously monitored for cerebral perfusion pressure and partial pressure of brain tissue oxygen for an average of ...

BACKGROUND Brain hypoxia (BH) can aggravate outcome after severe traumatic brain injury (TBI). Whether BH or reduced brain oxygen (Pbto(2)) is an independent outcome predictor or a marker of disease severity is not fully elucidated. OBJECTIVE To analyze the relationship between Pbto(2), intracranial pressure (ICP), and cerebral perfusion pressure (CPP) and to examine whether BH correlates wit...

A consecutive series of 100 severely blunt head injured subjects was followed up six years after trauma and the level of psychosocial reintegration was determined for 87 subjects. Three-quarters of the series were classified as demonstrating major disability, having either a Poor Reintegration (33%) or a Substantially Limited Reintegration (43%); the remaining one-quarter of the series attained...

BACKGROUND : Previous studies indicate that age, Glasgow Coma Scale score (GCS), arterial hypotension, computed tomography (CT) findings, and pupillary reactivity are strong predictors of outcome for patients with severe traumatic brain injury (TBI). However, the predictive validity of these variables has never been rigorously tested in patients from the developing world. The objective of this ...

Non-traumatic coma in childhood is an important pediatric emergency. It can result from a wide range of primary etiologies. Objective: To study the etiology and clinical profile of pediatric non-traumatic coma and to determine the clinical signs predictive of outcome. Setting: Pediatric emergency department (PED) at a tertiary care university teaching pediatric hospital from September 2007 to J...

BACKGROUND AND PURPOSE Functional outcome in patients with minor head injury with neurocranial traumatic findings on CT is largely unknown. We hypothesized that certain CT findings may be predictive of poor functional outcome. MATERIALS AND METHODS All patients from the CT in Head Injury Patients (CHIP) study with neurocranial traumatic CT findings were included. The CHIP study is a prospecti...

Aspects of reliability and validity of the Glasgow Outcome Scale were studied by examining outcome scale categories and cognitive test scores in 57 patients with severe closed head injury seen within 2 years of injury. Inter-rater reliability of a three and six point scale was high. The three point scale, unlike the six point, showed a significant statistical association with cognitive test sco...