PURPOSE To determine whether Heidelberg Retina Tomograph (HRT; Heidelberg Engineering, Dossenheim, Germany) classification techniques and investigational support vector machine (SVM) analyses can detect optic disc abnormalities in glaucoma-suspect eyes before the development of visual field abnormalities. METHODS Glaucoma-suspect eyes (n = 226) were classified as converts or nonconverts based...

PURPOSE To compare the visual fields (VFs) of preperimetric open angle glaucoma (OAG) patients (preperimetric glaucoma VFs, PPGVFs) with the VFs of healthy eyes, and to discriminate these two groups by using the Random Forests machine-learning method. METHODS All VFs before a first diagnosis of manifest glaucoma (Anderson-Patella's criteria) were classified as PPGVFs. Series of VFs were obtai...

OBJECTIVE To compare the macular ganglion cell complex (GCC) with peripapillary retinal fiber layer (RNFL) thickness map in glaucoma suspects and patients. SUBJECTS AND METHODS Forty participants (20 glaucoma suspects and 20 glaucoma patients) were enrolled. Macular GCC and RNFL thickness maps were performed in both eyes of each participant in the same visit. The sensitivity and specificity o...

The efficacy of intraocular pressure reduction in retarding the progression of glaucoma has been demonstrated. This review examines the potential for prognostic advantage for glaucoma suspects in reducing their optic nerve head exposure to elevated intraocular pressure associated with activities which have been shown to elevate intraocular pressure. In this observational study, patients examine...

BACKGROUND Progressive disc tilting and the development or enlargement of peripapillary atrophy (PPA) are observed during a myopic shift in children. This could be related to the changes around the optic nerve head during eyeball elongation. If the biomechanical properties at or around the optic nerve head are changed after exposure to elevated intraocular pressure (IOP) in glaucoma eyes, diffe...

PURPOSE To improve the neurological hemifield test (NHT) using visual field data from both eyes to detect and classify visual field loss caused by chiasmal or postchiasmal lesions. METHODS Visual field and clinical data for 633 patients were divided into a training set (474 cases) and a validation set (159 cases). Each set had equal numbers of neurological, glaucoma, or glaucoma suspect cases...