A 51 year old woman with arrhythmogenic right ventricular dysplasia had two types of ventricular tachycardia--(a) a regular and sustained tachycardia and with normal frontal plane axis on electrocardiography and (b) an irregular non-sustained tachycardia with a leftward frontal plane axis. Changes in the QRS complex were sometimes seen during the sustained ventricular tachycardia. The clinical,...

Primary and secondary malignant central nervous system (CNS) tumors are devastating invasive tumors able to give rise to many kinds of differentiated tumor cells. Glioblastoma multiform (GBM), is the most malignant brain tumor, in which its growth and persistence depend on cancer stem cells with enhanced DNA damage repair program that also induces recurrence and resists current chemo- and radio...

Age-related macular degeneration is a multiform disease of the macula, the region responsible for detailed central vision. In recent years, plenty of new knowledge of the pathogenesis of this disease has been obtained, and the treatment of exudative macular degeneration has greatly progressed. The number of patients with age-related macular degeneration will multiply in the following decades, b...

This study aims to determine whether there are important clinico-electrical differences between patients with temporal lobe epilepsy (TLE) secondary to mesial temporal sclerosis (MTS) and those with TLE secondary to a discrete temporal neocortical lesion (NL). The case histories, interictal EEG, seizure semiology, ictal EEG and postoperative outcome of 46 pathologically proven patients (31 MTS ...

cutis laxa is rare and hetrogenous group of disorders related to abnormalities in elastic tissue. it may be autosomal recessive, autosomal dominant, x linked or acquired. acquired cutis laxa has developed after a febrile illness, inflammatory skin disease such a lupus eryhymatosis or erythema multiform, amyloidosis, hypersensitivity reaction to penicillin and in infants born from women who were...

We used cesium chloride (CsCl) for electrophysiologic studies in canine hearts in vivo and in vitro to examine the mechanisms underlying ventricular arrhythmias that are related to prolonged repolarization. Cesium is known to depress normal ventricular automaticity and some experimental arrhythmias by blocking delayed outward currents and prolonging action potential duration. In 10 dogs in norm...

Many integrable hierarchies of differential equations allow a variational description, called Lagrangian multiform or pluri-Lagrangian structure. The fundamental object in this theory is not Lagrange function but $d$-form that integrated over arbitrary $d$-dimensional submanifolds. All such action integrals must be stationary for field to solution the problem. In paper we present procedure obta...

This paper introduces an explorative functional data analysis approach for the analysis of brain tumor contour functions deformation. A dataset of 15 patients affected by Gioblastoma multiform related to two different stages is analyzed. The purpose is to study the dynamic of a sequence of two sets of tumor contour functions related to the two stages, thus Principal Differential Analysis has be...