BACKGROUND To compare the prognostic value of estimated glomerular filtration rate, cystatin-C, an alternative renal biomarker, and their combination, in an outpatient population with heart failure. Estimated glomerular filtration rate is routinely used to assess renal function in heart failure patients. We recently demonstrated that the Cockroft-Gault formula is the best among the most commonl...

To determine the renal effects of inhibiting the uptake and subsequent metabolism of endogenous adenosine, dipyridamole, a nucleoside transport inhibitor, was infused intrarenally into anesthetized dogs. Dipyridamole (24 micrograms/kg per min) inhibited the cellular extraction of [14C]adenosine (72 +/- 3% vs. 9 +/- 3%) and elevated the excretion of endogenous adenosine (0.60 +/- 0.08 to 1.70 +/...

These guidelines have been adopted by the British Nuclear Medicine Society.

Kenton P Arkill ([email protected]) Klaus Qvortrup ([email protected]) Tobias Starborg ([email protected]) Judith M Mantell ([email protected]) Carlo Knupp ([email protected]) Charles C Michel ([email protected]) Steve J Harper ([email protected]) Andy HJ Salmon ([email protected]) John M Squire ([email protected]) Dave O Bates (Da...

OBJECTIVES To assess the effect of fasting Ramadan during the hottest month of the year in Riyadh, Saudi Arabia. MATERIALS AND METHODS This prospective cohort study was performed at the King Fahd National Guard Hospital in Riyadh, Saudi Arabia. We used the Modification of Diet in Renal Disease formula to estimate the glomerular filtration rate in renal transplant patients who fasted and did n...

BACKGROUND Rapid estimation of the renal function is widely used in clinical practice. METHODS The validity of rapid estimation of renal function as well as long-term changes in renal function from the Cockcroft-Gault formula for estimation of creatinine clearance or from serum creatinine measurements was evaluated against the 51Cr-EDTA plasma clearance technique in 36 type 2 diabetic patient...

Aim—To investigate factors that influence urinary tissue factor (uTF) measurements: glomerular permeability and filtration, tubular function, haematuria, and urine bacterial growth. Methods—uTF, protein creatinine index, glomerular filtration rate, retinol binding protein, N-acetyl-â-D-glucosaminidase (NAG) and urinary haemoglobin (uHb) were measured in patients with hypertension, diabetes mell...