Microglia are the resident macrophage population of the central nervous system (CNS) and are required for CNS development, homeostasis, and immune defense. Dysregulated microglial activity is involved in the pathogenesis of neuro-degenerative conditions and is the dominant driver of neuro-inflammatory diseases named “microgliopathies”. In this issue of The EMBO Journal, Goldmann et al reveal th...

T he main purpose of my study was to compare the i-care tonometer to the Goldmann in terms of accuracy. Obviously when it comes to measuring IOP, accuracy is the most important aspect of any method of tonometry. However, there are other things to consider... patient comfort, repeatability (both inter and intra-practitioner) and who can actually use the device. So not only did I record the IOP r...

The visual fields of 13 children aged 7 to 16 (mean 10.7 years) were assessed by oculokinetic perimetry (OKP), a technique where the field of vision is tested at reading distance using a simple chart, and the results compared with conventional Goldmann perimetry. Cooperation with testing was greater for OKP than Goldmann perimetry and in some cases OKP was better correlated with clinical findin...

A Christmas Carol is a novel by Charles Dickens full of social criticism and framed in the story majesty. This study aims to reveal structure relation Evangelical movement England during Victorian era. employs theory Genetic Structuralism Lucien Goldmann. The result analysis shows that ghosts can change characters, setting, plot because they deliver main idea novel, which enlightenment message ...

A clinical evaluation of a new electron ProTon tonometer was performed comparing the values of intraocular pressure (IOP) measured using this instrument with those determined by a similar instrument, Tono-Pen XL, and by Goldmann applanation tonometry. The mean IOP measured in 106 eyes with the ProTon tonometer was not significantly different from that determined with Goldmann applanation, while...