In this research, novel functionally graded Ni-P coating was deposited with electroless process. The content of phosphorus was controlled to change gradual through the thickness of the coating. During the plating, bath temperature and pH were changed at specified intervals to obtain functionally graded structure. To compare the properties of functionally graded coating with Ni-P single-layer co...

In recent years, honeycomb fiber reinforced plastic (FRP) sandwich panels have been increasingly used in various industries. Low weight, low price and high mechanical strength are the benefits of these structures. However, their mechanical properties and behavior have not been fully explored. The objective of this study is to conduct a combined numerical-statistical investigation of honeycomb F...

Wood has been used as a material to build mechanical structures for thousands of years. As a natural composite of cellulose fibers embedded in a matrix of lignin, this organic, cellular solid resists both tension and compression. Its properties depend on the direction of loading of its cells − whether radially, tangentially, or axially − and such anisotropy is modeled well as a regular honeycom...

With the emergence of grid computing environment, performance measurement, analysis and prediction of non-dedicated distributed systems have become increasingly important. In this study, we put forward a novel performance model for non-dedicated network computing. Based on this model, a performance prediction and task scheduling system called Grid Harvest Service (GHS), has been designed and im...

sandwich panel with central core honeycomb aluminum as one of the main shielding structures because of their high strength-to-weight ratio and improved energy absorption capacity, has been attracted the attention of many researchers and practitioners in recent years. this paper initiates and presents a new type of central core honeycomb formed by hydroforming process. the study is augmented by ...

Originally thought of as a stomach-derived endocrine peptide acting via its receptors in the central nervous system to stimulate food intake and growth hormone expression, ghrelin and its receptor (growth hormone secretagogue receptor (GHS-R)) are widely expressed in a number of organ systems, including cancer cells. However, the direct functional role of ghrelin and its receptor in tumors of c...

Both ghrelin and somatostatin (SST) inhibit glucose-stimulated insulin secretion (GSIS) from pancreatic β-cells, but how these independent actions are regulated has been unclear. The mechanism must accommodate noncanonical ghrelin receptor (GHS-R1a)-G-protein coupling to Gα(i/o) instead of Gα(q11) and dependence on energy balance. Here we present evidence for an equilibrium model of receptor he...

The inbred genetic hypercalciuric stone-forming (GHS) rats exhibit many features of human idiopathic hypercalciuria and have elevated levels of vitamin D receptors (VDR) in calcium (Ca)-transporting organs. On a normal-Ca diet, 1,25(OH)2D3 (1,25D) increases urine (U) Ca to a greater extent in GHS than in controls [Sprague-Dawley (SD)]. The additional UCa may result from an increase in intestina...

Frick KK, Asplin JR, Krieger NS, Culbertson CD, Asplin DM, Bushinsky DA. 1,25(OH)2D3-enhanced hypercalciuria in genetic hypercalciuric stone-forming rats fed a low-calcium diet. Am J Physiol Renal Physiol 305: F1132–F1138, 2013. First published August 7, 2013; doi:10.1152/ajprenal.00296.2013.—The inbred genetic hypercalciuric stone-forming (GHS) rats exhibit many features of human idiopathic hy...