BACKGROUND There are conflicting reports on the effect of donor-recipient HLA matching on outcomes in heart transplantation. The objective of this study was to investigate the effects of HLA-A matching relative to HLA-B and -DR matching on long-term survival in heart transplantation. METHODS A total of 25 583 patients transplanted between 1988 and 2011 were identified from the International S...

Polyetheretherketone (PEEK) is considered a potential material for replacing traditional biomedical metals used in orthopedic implants because of its similar elastic modulus to human bone. However, the poor osteogenic activity PEEK itself hinders clinical application. In this study, surface was grafted with poly (sodium vinylsulfonate) through single-step ultraviolet-initiated graft polymerizat...

Internal plasticization of poly(vinyl chloride) (PVC) was achieved in one-step using copper-mediated atom transfer radical polymerization to graft different ratios random n-butyl acrylate and 2–2-(2-ethoxyethoxy)ethyl copolymers from defect sites on the PVC chain. Five polymers were made with poly(butyl acrylate) (PBA) poly(2–2-(2-ethoxyethoxy)ethyl (P2EEA); glass transition temperatures (Tg) f...

BACKGROUND HLAMatchmaker is a recently developed computer-based algorithm to determine donor-recipient HLA compatibility at the molecular level. Originally designed for highly alloimmunized patients, this algorithm is based on the concept that immunogenic epitopes are represented by amino acid triplets on exposed parts of protein sequences of HLA-A, -B, and -C chains accessible to alloantibodie...

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