We analyzed data from the National Nosocomial Infections Surveillance (NNIS) System from 1986-2003 to determine the epidemiology of gram-negative bacilli in intensive care units (ICUs) for the most frequent types of hospital-acquired infection: pneumonia, surgical site infection (SSI), urinary tract infection (UTI), and bloodstream infection (BSI). We analyzed >410,000 bacterial isolates associ...

Francisella philomiragia is a Gram-negative coccobacillus, which very rare human opportunistic pathogen causing pneumonia and systemic infection. It difficult to identify this bacterium through conventional Gram-staining biochemical methods due an amorphous Gram stain appearance after 24 h culture its relatively fastidious slow growth giving weak and/or delayed reactions in tests. often misiden...

BACKGROUND Prediction of the species of pathogen among patients with sepsis within hours would be helpful in accelerating proper treatment. As a potential method of shortening the time to identification, this study considered the usefulness of measuring procalcitonin (PCT) to predict blood culture (BC) results. METHODS The authors retrospectively analyzed the data of patients with a diagnosis...

background :  nosocomial infections are considered as health issues that affect developed and poor countries. these infections can be transmitted to patients through hospital environment and equipments. the aim of this study was to evaluate the prevalence of gram-negative bacilli in the environment and the equipments of hospitals in the east of golestan province in 2015.   methods :  in this st...

The importance of oxidase-positive, nonfermentative, Gram-negative bacilli in a variety of pathological processes is becoming increasingly important. Oligella urethralis is an organism which is normally isolated as a commensal from the genitourinary tract. We have described one case of urinary tract infection caused by this organism. This isolated organism is found to be resistant to quinolones...

Methods This prospective randomized controlled study was carried out on 60 mechanically ventilated patients with gram negative VAP. Inclusion criteria: Adult mechanically ventilated patients diagnosed to have Gram negative VAP confirmed:· Radiologically (new chest xray infiltrate). · Microbiologically (positive culture from aspirate of endotracheal tube (ETT). · Clinically (fever, leukocytosis ...

The gram negative rod Acinetobacter baumannii is a soil and water saprophyte characterized by a high degree of innate and acquired antibiotic resistance. While it can colonize healthy hosts, it is also a well-established hospital-acquired pathogen, especially in intensive care and surgical units. The pathogen does not have many of the traditional virulence factors for producing disease in healt...

A full-length heme oxygenase gene from the gram-negative pathogen Neisseria meningitidis was cloned and expressed in Escherichia coli. Expression of the enzyme yielded soluble catalytically active protein and caused accumulation of biliverdin within the E. coli cells. The purified HemO forms a 1:1 complex with heme and has a heme protein spectrum similar to that previously reported for the puri...

Eikenella corrodens is a Gram-negative facultative anaerobe which is part of the normal human oropharyngeal flora and an opportunistic pathogen of mucous membrane tissues. We report a case of secondary E. corrodens ulcerative keratitis with hypopyon in a 39-year-old male with herpes simplex keratitis. To the best of our knowledge this is the first reported case of E. corrodens as a pathogen in ...

Campylobacter concisus, a member of the human’s oral microflora, is Gram-negative, fastidious, microaerophilic bacterium. However, it debatable whether should be recognised as commensal human cavity, or an opportunistic pathogen has been linked to and gastrointestinal infections. But there no doubt that its biofilm-forming capacity enhanced survival mechanism pathogen. Hence, through our invest...