tions in the phenotype, repertoire and activation status of lymphocytes as well as in the cytokine profile produced by these cells. As a lifelong condition, chronic parasitic diseases such as human schistosomiasis overlaps with the aging process and no systematic study has yet addressed the changes in immune response during infection with Schistosoma mansoni in older individuals. Aim : Herein w...

announce their intent to support a special awards competition opening in fiscal year 2002. For this awards competition, the EPA and the NSF are jointly soliciting grant applications that focus on the Decision-Making and Valuation for Environmental Policy (DMVEP) research area. The online announcement of the DMVEP awards competition and application forms are available at http://es.epa. gov/ncer/...

Background: Although sentinel lymph node (SLN) biopsy is a standard of care for the evaluation of the axillary lymph nodes during breast cancer surgery, a substantial degree of variation exists among individual surgeons as to what represents an adequate assessment. The aim of the current study was to assess when metastatic disease was first identified within consecutively harvested SLN candidat...

Obtaining research funding is of utmost importance for academic hematologists, especially those engaged in basic science research. Several funding mechanisms are available to researchers working in the fields of Hematology and/or Oncology. This chapter will discuss various issues relating to applications for National Institutes of Health (NIH) R01 grants, the classic funding mechanism for inves...

1 Epilepsy Center, University Hospital Freiburg, Freiburg, Germany, 2 Heidelberg Academy of Science and Humanities, Heidelberg, Germany, 3 Freiburg Brain Imaging, University Hospital Freiburg, Freiburg, Germany, 4 Bernstein Center for Computational Neuroscience Freiburg, Freiburg, Germany, 5 Neurobiology and Animal Physiology, Institute for Biology I, University of Freiburg, Freiburg, Germany, ...

The levels of mRNA for transforming growth factors (TGF alpha and beta) and the epidermal growth factor receptor (EGFR) were determined in 69 human breast carcinomas and 20 biopsies of nonneoplastic breast tissue by dot blot hybridisation analysis. TGF alpha mRNA was detected in 42% of cancers and 44% of non-neoplastic breast tissue at low levels. TGF beta mRNA was found in all breast cancers a...