نتایج جستجو برای: granulocyte colony stimulating factor g

تعداد نتایج: 1317676  

Journal: :The Yale Journal of Biology and Medicine 1990
B. R. Smith

Normal hematopoiesis is a well-regulated process in which the generation of mature blood elements occurs from a primitive pluripotent stem cell in an ordered sequence of maturation and proliferation. Regulation occurs at the level of the structured microenvironment (stroma), via cell-cell interactions and by way of the generation of specific hormones and cytokines: erythropoietin, interleukin 3...

Journal: :The Journal of Experimental Medicine 1990
Jonathan L. McQualter Rima Darwiche Christine Ewing Manabu Onuki Thomas W. Kay John A. Hamilton Hugh H. Reid Claude C.A. Bernard

Experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis, can be induced by immunization with a number of myelin antigens. In particular, myelin oligodendrocyte glycoprotein, a central nervous system (CNS)-specific antigen expressed on the myelin surface, is able to induce a paralytic MS-like disease with extensive CNS inflammation and demyelination in several strains of ...

Journal: :Infectious Diseases in Obstetrics and Gynecology 1995

2013
H. P. Koeffler

We show that 1,25-dihydroxyvitamin D3 (1,25[0H12D3), the most hormonally active metabolite of vitamin 113, modulates sensitively and specifically both the protein and messenger RNA accumulation of the multilineage growth factor granulocyte-macrophage colony-stimulating factor (GM-CSF). The regulation of GMCSF expression is seen in both normal human mitogen-activated T lymphocytes and T lymphocy...

2014
Anup Kasi Loknath Kumar Megha Teeka Satyan Jeffrey Holzbeierlein Moben Mirza Peter Van Veldhuizen

INTRODUCTION Granulocyte colony-stimulating factor produced by nonhematopoietic malignant cells is able to induce a leukemoid reaction by excessive stimulation of leukocyte production. Expression of granulocyte colony-stimulating factor and its functional receptors have been confirmed in bladder cancer cells. In vitro studies have demonstrated that granulocyte colony-stimulating factor/receptor...

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