نتایج جستجو برای: granulosa cel

تعداد نتایج: 7668  

2016
Catherine Bourguinat Hua Che Thangadurai Mani Kathy Keller Roger K. Prichard

Dirofilaria immitis is a filarial nematode causing infection and heartworm disease in dogs and other canids, cats, and occasionally in humans. Prevention with macrocyclic lactones (ML) is recommended during the mosquito transmission season. Recently, ML resistance has been reported. ABC-B transporter genes are thought to be involved in the mechanism of ML resistance in other nematodes. This stu...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2012
Jun-Hyeong Cho Ko Zushida Gleb P Shumyatsky William A Carlezon Edward G Meloni Vadim Y Bolshakov

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a pleiotropic neuropeptide expressed in the brain, where it may act as a neuromodulator or neurotransmitter contributing to different behavioral processes and stress responses. PACAP is highly expressed in the amygdala, a subcortical brain area involved in both innate and learned fear, suggesting a role for PACAP-mediated signaling i...

1999
PHILIP N. HOWLES GRANT N. STEMMERMAN CECILIA M. FENOGLIO-PREISER

Howles, Philip N., Grant N. Stemmerman, Cecilia M. Fenoglio-Preiser, and David Y. Hui. Carboxyl ester lipase activity in milk prevents fat-derived intestinal injury in neonatal mice. Am. J. Physiol. 277 (Gastrointest. Liver Physiol. 40): G653–G661, 1999.—Carboxyl ester lipase (bile saltstimulated lipase) is a pancreatic enzyme capable of hydrolyzing esters of cholesterol and fat-soluble vitamin...

2017
Christian Thaler Tanja Schneider Jan Sedlacik Daniel Kutzner Jan-Patrick Stellmann Christoph Heesen Jens Fiehler Susanne Siemonsen

PURPOSE In multiple sclerosis (MS) the sensitivity for detection of contrast enhancing lesions (CEL) in T1-weighted scans is essential for diagnostics and therapy decisions. The purpose of our study was to evaluate the sensitivity of T1w MPRAGE scans in comparison to T1w dark blood technique (T1-DB) for CEL in MS. MATERIALS AND METHODS 3T MR imaging was performed in 37 MS patients, including ...

2016
Karianne Fjeld Sebastian Beer Marianne Johnstone Constantin Zimmer Joachim Mössner Claudia Ruffert Mario Krehan Christian Zapf Pål Rasmus Njølstad Stefan Johansson Peter Bugert Fabio Miyajima Triantafillos Liloglou Laura J. Brown Simon A. Winn Kelly Davies Diane Latawiec Bridget K. Gunson David N. Criddle Munir Pirmohamed Robert Grützmann Patrick Michl William Greenhalf Anders Molven Robert Sutton Jonas Rosendahl

BACKGROUND Carboxyl-ester lipase (CEL) contributes to fatty acid ethyl ester metabolism, which is implicated in alcoholic pancreatitis. The CEL gene harbours a variable number of tandem repeats (VNTR) region in exon 11. Variation in this VNTR has been linked to monogenic pancreatic disease, while conflicting results were reported for chronic pancreatitis (CP). Here, we aimed to investigate a po...

Jafar Nasohi,

The granulosa cell tumor is the most common malignant functioning tumor of the ovary. When functional, granulosa tumor almost always are estrogenic although rare tumors are androgenic. Progesterone producing by these tumors has only been reported twice. We report a case of granulosa cell tumor in a 7 years old girl with precocious puberty who represent the first case of progesterone producing b...

2017
Bo Kang Dongmei Jiang Rong Ma Hui He Zhixin Yi Ziyu Chen

An increasing number of studies suggest that ornithine decarboxylase antizyme 1 (OAZ1), which is regarded as a tumor suppressor gene, regulates follicular development, ovulation, and steroidogenesis. The granulosa cells in the ovary play a critical role in these ovarian functions. However, the action of OAZ1 mediating physiological functions of granulosa cells is obscure. OAZ1 knockdown in gran...

2010
Tsung-Yeh Yang Yun-Min Sung Guang-Sheng Lei Tony Romeo Kin-Fu Chak

Carbon storage regulator (CsrA) is a eubacterial RNA-binding protein that acts as a global regulator of many functionally diverse chromosomal genes. Here, we reveal that CsrA represses expression from an extrachromosomal element of Escherichia coli, the lysis gene (cel) of the ColE7 operon (cea-cei-cel). This operon and colicin expression are activated upon SOS response. Disruption of csrA caus...

Journal: :Protein and peptide letters 2009
Keigo Hisamatsu Hideaki Unno Shuichiro Goda Tomomitsu Hatakeyama

The hemolytic lectin CEL-III and its site-directed mutants were expressed in Escherichia coli cells. Replacement of the valine clusters in domain 3 with alanine residues led to increased self-oligomerization in solution and higher hemolytic activity. The results suggest the involvement of these valine clusters in CEL-III oligomerization and hemolytic activity.

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