نتایج جستجو برای: growth differentiation factor 9b gdf9b

تعداد نتایج: 1620112  

Journal: :Cell reports 2012
Ek Han Tan Todd Blevins Thomas S Ream Craig S Pikaard

Multisubunit RNA polymerases IV and V (Pol IV and Pol V) evolved as specialized forms of Pol II that mediate RNA-directed DNA methylation (RdDM) and transcriptional silencing of transposons, viruses, and endogenous repeats in plants. Among the subunits common to Arabidopsis thaliana Pols II, IV, and V are 93% identical alternative ninth subunits, NRP(B/D/E)9a and NRP(B/D/E)9b. The 9a and 9b sub...

Journal: :Neurology - Neuroimmunology Neuroinflammation 2020

Ebrahim Zabihi, Hossein Ghanepour, Mahdieh Ghiasi, Mitra Narmashiri, Mohammad Mehdizadeh, Mohsen Sheykhhasan,

Introduction: Natural biomaterials and growth factors are key factors in tissue engineering. The objective of the present study was to evaluate transforming growth factor beta 1 (TGF-β1) and curcumin on proliferation and differentiation of nasal-derived chondrocyte seeded on the fibrin glue scaffold. Methods: Chondrocytes were isolated from nasal samples. Nasal-derived chon...

ژورنال: :پژوهش های آسیب شناسی زیستی 0
mojde pajokh department of anatomy, faculty of medical sciences, tarbiat modares university, tehran, iran mojdeh salehnia department of anatomy, faculty of medical sciences, tarbiat modares university, tehran, iran

هدف: عامل رشدی تمایزی 9b عامل رشد پروتئینی مشتق از تخمک است که بیان آن در تکوین فولیکول‏های تخمدان ضروری است. این عامل به‏واسطه گیرنده خود که بر سطح سلول‏ های گرانولوزا قرار دارد اثر خود را اعمال می کند. اثر عامل رشدی تمایزی 9b بر رشد فولیکول‏ های مراحل مختلف تکوینی به‏ویژه فولیکول‏ های بدوی و اولیه نا‏مشخص است. هدف از این مطالعه بررسی اثر عامل رشدی تمایزی 9b بر رشد فولیکول‏های مراحل مختلف تکوی...

1999
Srinivasa M. Srinivasula Manzoor Ahmad Yin Guo Yi Zhan Yuri Lazebnik Teresa Fernandes-Alnemri Emad S. Alnemri

Alternatively spliced isoforms of certain apoptosis regulators, such as Bcl-x, Ced-4, and Ich-1, have been shown to play opposing roles in regulating apoptosis. Here, we describe the identification of an endogenous alternatively spliced isoform of caspase-9, named caspase-9b, which lacks the central large subunit caspase domain. Caspase-9b is detectable in many cell lines by PCR and at the mRNA...

Journal: :The Biochemical journal 2008
Annika C Schüller Zamal Ahmed John E Ladbury

Two independent gain-of-function point mutations (S252W and P253R) in the extracellular region of the FGFR2 (fibroblast growth factor receptor 2) increase the binding affinity for the growth factor. The effect of this enhanced growth factor binding by these mutants is expected to be an increase in activation of regular signalling pathways from FGFR2 as a result of more receptors being engaged b...

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