OBJECTIVE To assess the accuracy of the determination of Helicobacter pylori infection by a stool immunoassay in patients with upper-gastrointestinal bleeding (UGB) of peptic origin, in comparison with the routine histological study, serology, rapid urease and 13C-breath tests. METHODS Sixty-eight patients with endoscopically proven UGB of peptic origin were included. The presence of H. pylor...

background: helicobacter pylori is a common cause of chronic infection in human beings. the infection has universal prevalence and contracts all age groups. probably, these bacteria are the cause of the most common chronic bacterial infection in man and have infected approximately half of the world population. the urease of these bacteria degrades the urea in stomach’s mucosa to ammoniac which ...

Background and Objective: Plantago psyllium has long been utilised as a medicinal agent worldwide. The current study aims to evaluate the in vivo antimicrobial effects of aqueous P. psyllium and a hydro-alcoholic extract of P. psyllium on Helicobacter pylori as well as the effects of these extracts on liver and kidney in a rat model. Materials and Methods: A total number of 50 female Sprague D...

Among several diagnostic tests, a Helicobacter pylori stool antigen (HpSA) test may offer a useful noninvasive method for diagnosing infection without sacrificing animals. In this study, male C57BL/6 mice (n=6) were infected with H. pylori ATCC 49503 (1×10(8) CFU/mouse) by intragastric inoculation three times at 2-day intervals, and H. pylori infected stool specimens were collected 1, 3, 5, 7, ...

Accurate noninvasive tests for diagnosing Helicobacter pylori infection in very young children are strongly required. We investigated the agreement between the [(13)C]urea breath test ([(13)C]UBT) and a monoclonal ELISA (HpSA) for detection of H. pylori antigen in stool. From October 2007 to July 2011, we enrolled 414 infants (123 from Brazil and 291 from Peru) of ages 6 to 30 months. Breath an...

Aim: This was a prospective, multicenter, single-arm intervention, against historical controls, study of the efficacy vonoprazan-based 7-day triple regimen with metronidazole (VPZ-AMPC-MNZ) as first-line therapy for eradicating clarithromycin-resistant Helicobacter pylori (H. pylori). Methods: We enrolled 35 patients positive H. pylori, assessed by culture, without history eradication. These we...

AIM To compare (1) demographics in urea breath test (UBT) vs endoscopy patients; and (2) the molecular detection of antibiotic resistance in stool vs biopsy samples. METHODS Six hundred and sixteen adult patients undergoing endoscopy or a UBT were prospectively recruited to the study. The GenoType HelicoDR assay was used to detect Helicobacter pylori (H. pylori) and antibiotic resistance usin...

Background and objectives: This study aims to detect the H. pylori infection in pediatric patients’ stool samples by using a multiplex urease PCR assay. Materials Methods: A retrospective analysis was performed test from sample of 55 patients evaluated August 2017 November 2018 compared with antigen histopathology. Results: Thirty-six (65%) were detected pylori-positive including nineteen boys ...

OBJECTIVE To determine whether Helicobacter pylori is associated with infantile colic. DESIGN Case-control study. SETTINGS Local tertiary hospital in rural Gizan, Saudi Arabia. PARTICIPANTS A total of 55 patients with infantile colic who were 2 weeks to 4 months of age and who fulfilled modified Wessel criteria (ie, crying and fussy behavior) and a total of 30 healthy controls with no his...