A series containing twelve substituted styryl 2-phenothiazenyl ketones have been synthesized. The electrochemical potentials of carbonyl and vinyl groups were measured. These potentials are correlated with Hammett substituent constants, F and R parameters. From the results of statistical analyses, the effects of substituent on the group reduction potentials have been discussed. The insect antif...

12 CLR 2015-2016 | MLO | www.clr-online.com Th e concept of critical values for drug levels was originally developed by the late Daniel M. Baer, MD, and fi rst published in the April 1982 issue of MLO. Th is table is an expanded version of that publication and newly revised for 2015-2016 by Catherine A. Hammett-Stabler, PhD, DABCC, FACB, Professor of Pathology, Director of Core Laboratories at ...

A catalytic, enantioselective formal synthesis of (+)-dichroanone and (+)-taiwaniaquinone H is reported. The all-carbon quaternary stereocenter was constructed by asymmetric conjugate addition catalyzed by a palladium(II) (S)-tert-butylpyridinooxazoline complex. The unexpected formation of a [3.2.1] bicyclic intermediate required the identification of a new route. Analysis of the Hammett consta...

Fractional factorial split-plot designs are widely used when it is impractical to perform fractional experiments in a completely random order. When there too many subplots per whole plot, or few plots, with replicated settings of the plot factors preferred. However, such an important study undeveloped literature. This paper considers WP from viewpoint clear effects. We investigate sufficient an...

In some experiments, the levels of factors are difficult to change; then fractional factorial split-plot (FFSP) designs suitable for selection. an FFSP design, divided into two classes—the whole plot (WP) and subplot (SP) factors. selection WP can affect that SP factors, which attracts much attention Paying more a new optimality criterion selecting such is proposed. The robustness proposed meth...

Three new protic ionic liquids based on 2-methylpyridinium were prepared and characterized. Their catalytic activities for the tert-butylation of phenol and the esterification of cyclic olefins with acetic acid were examined and satisfactory results were obtained over 2-methylpyridinium trifluoromethanesulfonate ([2-MPyH]OTf). Hammett method was used to determine the acidity order of these ioni...