نتایج جستجو برای: hcc
تعداد نتایج: 14224 فیلتر نتایج به سال:
context alpha-1-antitrypsin (a1at) is the most abundant liver-derived, highly polymorphic, glycoprotein in plasma. hereditary deficiency of alpha-1-antitrypsin in plasma (a1atd) is a consequence of accumulation of polymers of a1at mutants in endoplasmic reticulum of hepatocytes and other a1at-producing cells. one of the clinical manifestations of a1atd is liver disease in childhood and cirrhosi...
Abstract Background Hepatocellular carcinoma (HCC) can grow in a mosaic pattern, often combined with various non-hepatocellular cells. However, HCC neuroendocrine (NEC) component is rarely reported, and its clinical features, origin, diagnosis, behavior have not been established. In the literature, mixed HCC–NEC tumors are categorized as either collision type or type, depending on their microsc...
With an expected incidence of more than 1 million cases by 2025, liver cancer remains a problem for world health. over 90% cases, hepatocellular carcinoma (HCC) is the most prevalent kind cancer. In this review, we presented range experimental therapeutics patients with advanced HCC, successes and failures new treatments, areas future development, evaluation dose-limiting toxicity in different ...
Abstract Some studies have reported that activated ribosomes are positively associated with malignant tumors, especially in hepatocellular carcinoma (HCC). The RNA-binding protein PNO1 is a critical ribosome rarely human tumors. This study aimed to explore the molecular mechanisms of HCC. Using 150 formalin-fixed and paraffin-embedded samples 8 fresh samples, we found high expression HCC tumor ...
BACKGROUND The incidence of hepatocellular carcinoma (HCC) continues to increase in Japan, but the clinical characteristics of Japanese patients with HCC have not been well described. The aim of this study was to determine the frequencies and utilities of elevated a-fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP) levels as biomarkers in cryptogenic HCC. MATERIAL/METHODS A total of 2...
Abstract Background The potential correlation between H2AFY (also known as MacroH2A1) and the clinical characteristics of hepatocellular carcinoma (HCC) patients was analysed through gene expression profiles data in Cancer Genome Atlas (TCGA) database, diagnostic prognostic value HCC discussed. Methods corresponding were downloaded from TCGA database. differences normal liver tissues analysed. ...
BACKGROUND We investigated the patterns and predictors of recurrence and survival in cryptogenic non-B, non-C, non-alcoholic hepatocellular carcinoma (CR-HCC). We compared the findings with those hepatitis virus B (B) and hepatitis virus C (C)-HCC. CR-HCC does not include HCC developed on NASH. METHODS From 1990 to 2011, of 676 patients who underwent primary curative liver resection as initia...
The incidence of hepatocellular carcinoma (HCC) in Japan is still increasing. The aim of the present study was to analyze the epidemiological trend of HCC in the Western area of Japan, Nagasaki. A total of 1,807 patients with HCC diagnosed at our two hospitals between 1981 and 2005 were consecutively recruited for this study. Cohorts of patients with HCC were categorized into five-year interval...
Anatomical resection (AR) has been reported to achieve better long-term outcomes than non-anatomical for the treatment of hepatocellular carcinoma (HCC). The surgical feasibility and oncological significance laparoscopic AR (LAR), especially “subsegment resection”, “cone unit repeat LAR HCC, remain unproven. We present a 67-year-old patient with alcoholic liver cirrhosis HCC who underwent full ...
BACKGROUND AND AIMS Deletions/mutations in the hepatitis B virus (HBV) pre-S region have been associated with hepatocellular carcinoma (HCC). We aimed to study the evolutionary changes of pre-S mutations prior to HCC development. METHODS We studied the HBV pre-S sequences at 1 to 10 years preceding diagnosis of HCC in 74 patients with HBV-related HCC (HCC group). 148 chronic hepatitis B patie...
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