HDL plays an initial role in reverse cholesterol transport by mediating cholesterol removal from cells. During infection and inflammation, several changes in HDL composition occur that may affect the function of HDL; therefore, we determined the ability of acute-phase HDL to promote cholesterol removal from cells. Acute-phase HDL was isolated from plasma of Syrian hamsters injected with lipopol...

Analysis of structural and functional parameters of HDL has gained significant momentum in recent years because they are stronger predictors of cardiovascular risk than HDL-cholesterol levels. Surprisingly, in most HDL studies, very low attention is paid to HDL storage, which might critically affect functional properties. In the present study, we systematically examined the impact of storage an...

High-density lipoprotein (HDL) cholesterol has been known for ages to be cardio-protective due its defensive action against genesis of atherosclerosis. Increasing the serum HDL (HDL-C) as a prospective potential prevent coronary heart disease could not prove beneficial in human trials that put forward major concern about role and functional contribution HDL-C health. Many observational studies ...

Dictionary learning has been an important role in the success of data representation. As a complete view representation, hybrid dictionary (HDL) is still its infant stage. In previous HDL approaches, scheme how to learn effective for image classification not well addressed. this paper, we proposed locality preserving and label-aware constraint-based (LPLC-HDL) method, apply it effectively. More...

BACKGROUND Inhibition of cholesteryl ester transfer protein (CETP) is an efficient way to increase high-density lipoprotein (HDL) levels in humans. We investigated the effects of the inhibition of CETP activity by a CETP inhibitor, JTT-705, on the function and composition of HDL particles. METHODS AND RESULTS Japanese white rabbits were fed either normal rabbit chow LRC-4 (n=10) or a food adm...

RATIONALE Coronary endothelial dysfunction (ED)-an early marker of atherosclerosis-increases the risk of cardiovascular events. OBJECTIVE We tested the hypothesis that cholesterol efflux capacity and high-density lipoprotein (HDL) particle concentration predict coronary ED better than HDL-cholesterol (HDL-C). METHODS AND RESULTS We studied 80 subjects with nonobstructive (<30% stenosis) cor...

This study aimed to estimate the relationship between various lipid abnormalities and albuminuria in hypertensive Korean adults. Data obtained from the Korea National Health and Nutrition Examination Survey in 2011 to 2012 were analyzed. The study included 2330 hypertensive participants. Total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lip...

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STUDY QUESTION Is polycystic ovary syndrome (PCOS) associated with altered levels of pro-inflammatory high-density lipoproteins (HDL) and activity of HDL-associated enzymes? SUMMARY ANSWER In PCOS, HDL contained increased levels of the inflammatory marker serum amyloid A (SAA) and altered functioning of HDL-associated phospholipid transfer protein (PLTP), with these changes being independent ...