BACKGROUND Iron deficiency is common in patients with heart failure (HF) and is associated with reduced exercise capacity and poor outcomes. Whether correction of iron deficiency with (intravenous) ferric carboxymaltose (FCM) affects peak oxygen consumption [peak VO2], an objective measure of exercise intolerance in HF, has not been examined. METHODS We studied patients with systolic HF (left...

By Fru rn mci A. Kur’sitm t m JoHN Li Er AUM S INCE THE INITIAL case reports in 1949,1,2 the occurrence of megaloblastic anemia as a complication of alcoholic cirrhosis has been reported with increasing frequency in recent years.314 Jarrold and Vilter reviewed the marrows of 30 patients with cirrhosis and found 3 to be megaloblastic.1 Krasnow et al. found the incidence of megaloblastic anemia i...

By Fru rn mci A. Kur’sitm t m JoHN Li Er AUM S INCE THE INITIAL case reports in 1949,1,2 the occurrence of megaloblastic anemia as a complication of alcoholic cirrhosis has been reported with increasing frequency in recent years.314 Jarrold and Vilter reviewed the marrows of 30 patients with cirrhosis and found 3 to be megaloblastic.1 Krasnow et al. found the incidence of megaloblastic anemia i...

F. H. CHEN is a kind of herb belongs to Acanthopanax Gracilistylus with synonym of stephania sinica and pseudoginsen radix. It has been considered to be one of the famous traditional Chinese medicinal herbs in China or other oriental countries for thousands of years. San-Chi contains many of chemical constituents. Total panax notoginsenoside (TPNS), isolated from San-Chi is a mixture of more th...

BACKGROUND Medicinal plants have proven their importance as a valuable source of molecules with therapeutic potential. Monotheca buxifolia (Falc.) A. DC. (family: Sapotaceae) is traditionally used as a hematinic, laxative, digestive, anthelmintic, antipyretic, and in the treatment of gastro-urinary disorders. To provide scientific evidence for its folkloric use, the present study investigated M...

OBJECTIVE Patients with diabetes commonly have a greater degree of anemia for their level of renal impairment than those presenting with other causes of renal failure. To clarify the contribution and differing roles of diabetes and nephropathy in the development of anemia in diabetic patients, we examined the hematologic and hematinic parameters of diabetic patients without nephropathy. RESEA...

Proton pump inhibitors (PPIs) block acid production through H/K ATPase inhibition which is the final pump in the acid secretion pathway. They are generally well tolerated in the short term both in adults and children. However, prolonged suppression of acid secretion may interfere with absorption of various minerals, vitamins, and hematinic factors [1]. Although parietal cells are the major site...

The management of the rare, life threatening and chronic disease, paroxysmal nocturnal hemoglobinuria (PNH) was revolutionized by introduction terminal complement inhibitor therapy, eculizumab (Soliris), which licensed in 2007.1 Since that time, numerous studies have highlighted improvement organ damage on a C5 inhibitor, such as reduction thrombotic events, renal function pulmonary hypertensio...

Rx Only (sodium ferric gluconate complex in sucrose injection) DESCRIPTION Ferrlecit (sodium ferric gluconate complex in sucrose injection) is a stable macromolecular complex with an apparent molecular weight on gel chromatography of 289,000 – 440,000 daltons. The macromolecular complex is negatively charged at alkaline pH and is present in solution with sodium cations. The product has a deep r...