Fasting blood glucose measurements were made using the hexokinase method in a Cobas 6000 (Roche Diagnostics, Rotkreuz, Switzerland). Determinations of HbA1c were performed on ethylenediaminetetraacetic acid–anticoagulated blood sample by two methods: high-performance liquid chromatography (HPLC) (HA-8160 in diabetic mode, A. Menarini Diagnostics, Florence, Italy), which detected no abnormal hem...

INTRODUCTION Glycated hemoglobin (HbA1c) can be altered in different conditions. We hypothesize that HbA1c levels may change due to altered thyroid status, possibly due to changes in red blood cell (RBC) turnover. OBJECTIVES The objective of this study was to determine the effects of altered thyroid status on HbA1c levels in individuals without diabetes, with overt hyper- and hypo-thyroidism,...

abstract background and objective: diabetes mellitus is one of complications that thalassemia major patients face with. hence, blood glucose monitoring is of vital importance to these patients. because of high level of fetal hemoglobin in these patients, the measurement of hemoglobin a1c is not reliable and should be displaced by fructosamine test. material and methods: the current descriptive ...

OBJECTIVE To study the influence of glycemic control and the presence of microalbuminuria on the initial response to panretinal photocoagulation (PRP) in patients with a high-risk proliferative diabetic retinopathy (PDR). RESEARCH DESIGN AND METHODS This was a prospective cohort study with a two-by-two factorial design. We used full-scattered PRP to treat 115 eyes of type 2 diabetic patients ...

Obesity-related inflammation-induced insulin resistance and metabolic dysregulation were investigated in retrospective analysis of placebo hematologic and metabolic laboratory data from trials associated with increasing chronic low-grade inflammation and body mass index. Studies included healthy subjects and those with progressive stages of metabolic dysregulation, including type 2 diabetes mel...

Hemoglobin A1c (HbA1c) is the gold-standard measure for diagnosing and managing diabetes. Given importance of data-driven decisions, this paper aimed to develop a method elucidating predicting HbA1c levels. We developed comprehensive analyzing multiple linear regression through R syntax, embedding multilayer feedforward neural networks (MLFFNN) bootstrapping. The success proposed was determined...

Abstract Objective The study sought to investigate whether consistent use of the Veterans Health Administration’s My HealtheVet (MHV) online patient portal is associated with improvement in diabetes-related physiological measures among new users. Materials and Methods We conducted a retrospective cohort users type 2 diabetes that registered for MHV between 2012 2016. used random-effect linear r...

The HNF1A transcription factor, implicated in the regulation of pancreatic beta cells, as well glucose and lipid metabolism, is responsible for type 3 maturity-onset diabetes young (MODY3). also involved increased susceptibility to polygenic forms diabetes, such 2 (T2D) gestational (GD), while its possible role 1 (T1D) not known. In this study, 277 children adolescents with T1D 140 healthy cont...

Objective: Atrial fibrillation (AF) is the most common cardiac arrhythmia seen after coronary artery bypass(CABG) surgery. Hemoglobin A1c (HbA1c) levels known to have correlation with developement of post operative atrial (POAF) CABG In our study we investigated predictability preoperative HbA1c for postoperative POAF in patients who underwent isolated on-pump operation clinic. Method: We retro...

BACKGROUND The ratio of glycated albumin to glycated hemoglobin (GA/A1c) is known to be elevated in subjects with type 2 diabetes mellitus (T2DM) who had decreased insulin secretion. Additionally, the carotid intima media thickness (IMT) is greater in T2DM patients with higher GA/A1c ratios. We investigated whether increased GA/A1c ratio and IMT are also associated in type 1 diabetes mellitus (...