Hepatitis B vaccination strategies may vary from country to country depending on hepatitis B virus (HBV) endemicity, predominant modes of infection, age of infection, and health care resources. In areas with high endemicity like Korea, transmission of virus from carrier mothers to infants during the perinatal period, and from other horizontal sources to infants and children, account for most ca...

INTRODUCTION Tuberculosis (TB) affects one-third of the world's population. Anti-TB drugs with isoniazid, rifampicin and pyrazinamide are very effective but they can cause hepatotoxicity. Many risk factors have been recognised. Data on prevalence of anti-TB drug-induced hepatitis as well as the contributing risk factors are scarce in Malaysia. This observational case control study was designed ...

Thyroid hormone levels were estimated in fifty patients with hepatitis B. In acute phase, T3 was raised in 10% and T4 in 60%. This rise was directly proportional to the transaminases levels. Twenty cases were also studied in the recovery phase where thyroid hormones returned to within normal limits. This rise of T3 and T4 in acute phase is attributed to increased thyroxin binding capacity due t...

MASSIVE pulmonary embolism (PE), although an uncommon complication in liver transplant surgery is associated with a high mortality rate. Five of nine patients reported to have massive PE in the past 12 yr died from this complication. We report a case of PE that occurred in the same patient during two consecutive liver transplant procedures in association with the use of an antifibrinolytic and ...

Haemophilus influenzae type b (Hib) is the leading cause of meningitis in children < 5 years of age. The majority of cases of Hib occur in infants < 2 years of age. Until recently the only vaccine available against this disease contained the pure polysaccharide (PRP) of Hib (Hib-PRP vaccine). The Hib-PRP vaccine was demonstrated to be efficacious in infants > 18 months of age but not below that...